Chu, H.M.; Fisher, W.F.; Osborne, T.; and Comb, M.J. NF-1 proteins from brain 
interact with the proenkephalin cAMP inducible enhancer. Nucleic Acids Res 
19:2721-2728,1991. 
Comb, M.; Birnberg, N.C.; Seashoitz, A.; Herbert, E.; and Goodman, H.M. A 
cyclic AMP- and phorbol ester-inducible element. Nature 323:353-356, 1986. 
Comb, M.; Mermod, N.; Hyman, S.E.; Pearlberg, J.; Ross, M.E.; and Goodman, 
H.M. Proteins bound at adjacent DNA elements act synergistically to 
regulate human proenkephalin cAMP inducible transcription. EMBO J 
7:3793-3805, 1988. 
Dragunow, M.; Robertson, G.S.; Faull, R.L.M.; Robertson, H.A.; and Jansen, K. 
D 2 dopamine receptor antagonists induce fos and related proteins in rat 
striatal neurons. Neuroscience 37:287-294, 1990. 
Dragunow, M., and Robertson, H.A. Kindling stimulation induces c-fos proteins 
in granule cells of the rat dentate gyrus. Nature 329:441 -442, 1 987. 
Fisch, T.M.; Prywes, R.; and Roeder, R.G. C-fos sequences necessary for 
basal expression and induction by epidermal growth factor, 12-0- 
tetradecanoyl phorbol-1 3-acetate, and the calcium ionophore. Mol Cell 
Biol 7: 3490-3502, 1987. 
Fisch, T.M.; Prywes, R.; Simon, M.C.; and Roeder, R.G. Multiple sequence 
elements in the c-fos promoter mediate induction by cAMP. Genes Dev 
3:198-211,1989. 
Gall, C. Seizures induce dramatic and distinctly different changes in 
enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal 
mossy fibers. J Neurosci 8:1 852-1 862, 1988. 
Gilman, M.Z. The c-fos serum response element responds to protein kinase 
C-dependent and -independent signals but not to cyclic AMP. Genes Dev 
2:394-402, 1988. 
Graybiel, A.M.; Moratalla, R.; and Robertson, H.A. Amphetamine and cocaine 
induce drug-specific activation of the c-fos gene in striosome-matrix 
compartments and limbic subdivisions of the striatum. Proc Natl Acad Sci 
USA 87:6912-6916, 1990. 
Hayward, M.D.; Duman, R.S.; and Nestler, E.J. Induction of the c-fos proto- 
oncogene during opiate withdrawal in the locus coeruleus and other regions 
of the brain. Brain Res 525:256-266, 1990. 
Hope, B.; Kosofsky, B.; Hyman, S.E.; Nestler, E.J. Regulation of IEG 
expression and AP-1 binding by chronic cocaine in the rat nucleus 
accumbens. Proc Natl Acad Sci USA, in press. 
Hyman, S.E.; Comb, M.; Lin, Y.S.; Pearlberg, J.; Green, M.R.; and Goodman, 
H.M. A common trans-acting factor is involved in transcriptional regulation 
of neurotransmitter genes by cyclic AMP. Mol Cell Biol 8:4225-4233, 1988. 
Hyman, S.E.; Comb, M.; Pearlberg, J.; and Goodman, H.M. An AP-2 element 
acts synergistically with the cyclic AMP- and phorbol ester-inducible 
enhancer of the human proenkephalin gene. Mol Cell Biol 9:321 -324, 1 989. 
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