TABLE 1 . A list of representative eariy-response genes* 
Gene 
Possible Function 
References 
C -myc 
Transcriptional modulator? 
Helix loop helix 
Kelly et al. 1983; Murre et al. 1989 
JE 
Cytokine 
Cochran et al. 1983; Rollins et al. 
1988 
KC, MGSA, gro 
Cytokine 
Anisowicz et al. 1987; Cochran et al. 
1983; Richmond et al. 1988 
C-fos 
Transcription factor 
Leucine zipper 
Cochran et al. 1984; Greenberg and 
Ziff 1984; Kruijer et al. 1984; Muller 
et al. 1984 
FraA 
Transcription factor 
Leucine zipper 
Cohen and Curren 1 988 
Fos- B 
Transcription factor 
Leucine zipper 
Zerial et al. 1989 
Zif/ 268, egrA , 
TIS8, KROX24, 
NGFIA 
Transcription factor 
Zinc finger 
Christy et al. 1988; Lemaire et al. 
1988; Milbrandt 1987; Sukhatme 
et al. 1988 
KROX20, egr-2 
Transcription factor 
Zinc finger 
Chavrier et al. 1989 
NGFIB, TIS1 , 
nufJl 
Steroid receptor 
Superfamily 
Hazel et al. 1988; Milbrandt 1988 
C -jun 
Transcription factor 
Leucine zipper 
Lamph et al. 1988; Ryder and 
Nathans 1 988 
JurhB 
Transcription factor 
Leucine zipper 
Ryder et al. 1988 
p-actin 
Cytoskeletal component 
Greenberg and Ziff 1984 
SRF 
Transcription factor 
Norman et al. 1988 
2'-5' oligo- 
adenylate 
synthetase 
Enzyme 
Garcia-Bianco et al. 1989 
Rho-B 
Ras-like G protein 
Jahner and Hunter 1 991 a 
*For a more comprehensive list, see Herschman (1991). 
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