Appendlx D. 
195 
IV. Oversight 
A. The NTH Human Pluripotent Stem Cell Review Group (HPSCRG) 
will review documentation of compliance with the Guidelines for 
funding requests that propose the use of human pluripotent stem 
cells. This working group will hold public meetings when a funding 
request proposes the use of a line of human pluripotent stem cells 
that has not been previously reviewed and approved by the 
HPSCRG. 
B. In the case of new or competing continuation (renewal) or 
competing supplement applications, all applications shall be 
reviewed by HPSCRG and for scientific merit by a Scientific Review 
Group. In the case of requests to use existing funds or applications 
for an administrative supplement or in the case of intramural 
proposals, Institute or Center staff should forward material to the 
HPSCRG for rethew and determination of compliance with the 
Guidelines prior to allowing the research to proceed. 
C. The NTH will compile a yearly report that will include the 
number of applications and proposals reviewed and the titles of all 
awarded applications, supplements or administrative approvals for 
the use of existing funds, and intramural projects. 
D. Members of the HPSCRG will also serv’e as a resource for 
recommendations to the NTH with regard to any revisions to the NTH 
Guidelines for Research Using Human Pluripotent Stem Cells and any 
need for human pluripotent stem cell policy conferences. 
Dated: August 17, 2000. 
Ruth L. Kirschstein, 
Principal Deputy Director, NTH. 
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PRE -PUBLICATION VERSION 
