chapter 4 
Page 
Background 59 
Past Uses of Genetics 59 
Potential Uses of Molecular Genetic Technologies 61 
Hormones 61 
Insulin 65 
Growth Hormone 67 
Other Hormones 67 
Immunoproteins 68 
Antigens (Vaccines) 68 
Interferons 70 
Lymphokines and Cytokines 7l 
Antibodies 71 
Enzymes and Other Proteins 72 
Enzymes 72 
Other Proteins 74 
Antibiotics 75 
Nonprotein Pharmaceuticals 76 
Impacts 77 
Technical Notes 80 
Tables 
Table No. Page 
3. Large Human Polypeptides Potentially 
Attractive for Biosynthesis 61 
Table No. Page 
4. Naturally Occurring Small Peptides of 
Potential Medical Interest 64 
5. Summary of Potential Methods for 
Interferon Production 70 
6. Immunoassays 73 
7. Diseases Amenable to Drugs Produced by 
Genetic Engineering in the Pharmaceutical 
Industry 78 
8. Major Diseases for Which Vaccines Need To 
Be Developed 78 
Figures 
. Figure No. Page 
20. The Development of a High Penicillin- 
Producing Strain via Genetic Manipulation . . 60 
21. The Product Development Process for 
Genetically Engineered Pharmaceuticals .... 63 
22. The Amino Acid Sequence of Proinsulin .... 65 
23. Recombinant DNA Strategy for Making 
Foot-and-Mouth Disease Vaccine 69 
