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feem to have acquired fuch a bulk, or were become 
fo rough or pointed in their furface, as to occafion 
great pain, frequent provocations to urine, and fome- 
times bloody urine ; efpecially after any confiderable 
motion. Thefe complaints, however, were foon re- 
lieved, by fwallowing daily an ounce of Alicant 
foap, and three Englifh pints of lime-water mads 
with calcined oyfter-fhells : and from 1748 to 1757 
his Lordfihip was kept almoft intirely free from any 
return of them, except for fome months of 17 fo 
and 175*1, during which he took only one-third 
part of the quantity of foap and lime-water above- 
mentioned (2). 
a. It is highly probable, nay, I think, altogether 
certain, that the foap and lime-water not only re- 
lieved Lord Walpole of the painful fymptoms occa- 
sioned by the ftones in his bladder, but alfo prevented 
their increafe. 
If thefe hones came into the bladder in 1734, 
they muft, in fo many years as his Lordftfip lived 
after this, have acquired a very great bulk : nay, if we 
fuppofe them not to have been lodged in the bladder 
above a year before they began to occafion frequent 
inclination to make urine, with pain, and fometimes 
fudden ftoppages of urine; yet, from 1746 to 175*7, 
they ought to have grown to a much larger fize 
than that of the kernel of a Spanifh nut {3), J Tis 
(2) Philofoph. Tranfaft. Vol. xlvii. p. 48 and 473. and Eflay 
on Lime-water, p. 157 and 200. 
(3) The two ftones found in Lord Walpole’s bladder were of 
this fize, and weighed one of them 22 and the other 21 grains. 
E e 2 true. 
