[ 2I 7 ] 
bladder was almoft as thick fet with (harp prickles, 
as the back of an hedgehog : fo that, in this cafe, no 
remarkable eafe could be procured to the patient by 
the medicines, until they had quite diflolved thefe 
fharp points, and rendered the furface of the ftone 
fmooth and equal ; which was not to be done but 
after a very long time, especially as the ftone was of 
a pretty hard texture. 
It may be proper to take notice, that when, along 
with the ftone, there is any ulceration in the bladder, 
foap does mifchief, and lime-water often fails of 
giving any confiderable relief. However, even in this 
cafe it is perhaps one of the beft remedies we know. 
5. Soap and lime-water, taken in large quantities* 
and perftfted in for many years together, appear to 
be innocent, and no way injurious to health. 
Lord Walpole, who ufed thefe medicines for up- 
wards of eight years, was not only relieved of the 
painful fymptoms of the ftone, but had his health 
improved by them in other refpedts (12). His ap- 
petite, healthful look, and a degree of fpirits un- 
common at his age, continued till the end of ly yd, 
when his laft illnefs began firft to attack him. And 
as his health did not appear to be any way injured by 
thefe medicines ; fo, when his body was opened aftet 
death, his kidneys and ureters were obferved to be 
quite found and natural, as was likewife his bladder j 
only its coats appeared a little thicker than ufual, 
Owing probably to the long-continued fridtion of the 
ftones upon it. Neither the kidneys, ureters, nor 
(12) Eflay on Lime-water, &V. ad edit. p. 171, 201. 
Vol. 50, Ff bladder* 
