[ 345 ] 
taking cold, or any irregularity in the non-na f u r a!s, 
he became weaker, breathed fhorter, efpecially upon 
walking a little, or talking rather moie 01 higher than 
ufual, any of which exertions put him out of breath 
prefently. 
When he firft applied to me, in the beginning of 
March 1761, I found him labouring under the above- 
mentioned complaints j and upon examining his pulfe, 
found it loft, and extremely quick : it commonly 
went at the rate of 1 10 in the morning, and in the 
evening 120, pulfations in a minute, as I repeatedly 
obferved. The palpitation ot the heart ftruck me in- 
ftantly, as it ftiook his whole body at every ftroke. 
I could never obferve any inequality of the intermittent 
kind in the pulfe, under any the moft accelerated 
motion thereof, or in whatfoever fituation the body 
was placed. 
At this time the chylopoietic organs were ail to- 
lerably good. Stimulating food, or fermented liquors, 
had, for fome time, always increafed his anxiety and 
load upon his bread:, and this experience had induced 
him to refrain from them. 
He had flept very ill for feveral months, fome- 
times not more than an hour or two during the whole 
courfe of the night. He could not fleep on the left 
fide at all, and was always eafieft in an eredt pofture. 
He was commonly awaked with a fenl'e of fuffoca- 
tion, from the vaft load and oppreffion upon his 
bread, and from the ftrength of the palpitation. 
From his firft application to me, I had no hopes 
of doing him any real fervice, as I thought it evident, 
from his complaints, and particularly from the great 
and uninterrupted palpitation, and the feel ot the 
Vol. LII. Y y pulfe, 
