1930 ] 
Development of Dermatobia hominis 
331 
Newcastle when I allowed the two larvae to enter my left 
arm, since I evidently was already infested with four of 
them at the time. It is quite certain that these four larvae 
were deposited on me by the carrier fly while it was alight- 
ing on me just prior to its capture. This placed their 
entrance into my skin at about six hours earlier than when 
the two entered my left arm. Finding myself now infested 
with six of the larvae I decided to allow them all to remain 
until they began to produce too great a reaction, either 
local or general. In order to record observations on the 
larvae each one was given a number. The two on the 
left arm were numbered 1 and 2 ; the one at the right wrist 
was No. 3, in the right forearm No. 4, in the upper right 
leg No. 5, and below the right knee as No. 6. Nos. 1, 2, 4 
and 5 were located in areas surrounded by considerable 
adipose and muscular tissues, while Nos. 3 and 5 were in 
situations surrounded mainly by fibrous tissue and with 
much less softer tissues. 
October 16. Each lesion, or site of each larva, now ap- 
pears as a bright red area, about three-eighths of an inch 
in diameter, and slightly elevated in the center. There is 
sufficient itching and pricking occurring to cause consider- 
able discomfort. The irritation seems to be much greater 
during the evenings and nights than throughout the days. 
No. 6 proves an exception to this, since there is frequently 
a prolonged stinging or burning sensation experienced when 
I am walking. While I am at rest this larva seldom causes 
any annoyance. ' No. 4 seems to be causing the greatest 
irritation. This may be due to the location of this lesion 
on the lower surface of my right forearm, and thus sub- 
jected to considerable rubbing on desk and tables while I 
am at work. 
October 17. Last night I was awakened by a severe itch- 
ing and dull burning sensation at No. 4. The burning 
sensation seemed to feel more like an erosive burn caused 
by a strong acid than to contact with a hot surface. All 
the lesions are exuding serous fluid at times. That which 
comes from Nos. 1 and 4 is slightly tinged with blood. 
October 18. Last night the lesions on both arms became 
very irritating and awakened me several times. There 
has also been considerable itching and pain today. 
