1930 ] 
Development of Dermatobia hominis 
337 
This may be due to absorption of toxins from the lesions 
and may also be influenced by the many times that I am 
awakened each night by the larvae. The lesions are now 
emitting a fetid odor which becomes very disagreeable if 
the bandages are not changed frequently. When they re- 
main unchanged during the night the odor is extremely 
offensive in the morning. 
November 1U- During the night I was awakened by a 
severe pain in No. 3 and a contraction of the muscles of 
the wrist and forearm. This served to draw my hand 
back on the wrist, and I was unable to straighten the hand 
except by using my left hand. It was necessary to place 
the hand and wrist in cold water before relief was afforded. 
Considerable blood and serum oozed from this lesion fol- 
lowing the pain and contraction. During the past few 
days this lesion has become much swollen and is very red 
and inflamed. The center of the lesion is taking on a dark 
purple appearance, although the aperture is well down on 
one side near the base of the swelling. 
November 17. No. 5 is very painful and the muscles 
of the leg are stiff and sore to the touch, and is causing 
some lameness. All the lesions are oozing considerable 
serum and pus. I seemed to be quite feverish at one time 
when I awakened last night, but the feeling of lassitude 
was so great that no temperature was taken. 
November 19. No. 3 has been causing severe pain and 
muscular contraction at intervals during the past four days 
and the wrist is very painful. No. 6 has been quite sore 
for several days, and this evening it was found that an- 
other opening had developed in it. This new opening is 
located on the side opposite the original opening and about 
where the anterior end of the larva seems to be. It is a 
question whether this second aperture is due to action of 
the oral hooks of the larva or to sloughing caused by pus 
inside the lesion. 
November 20. No. 3 awakened me several times during 
the night by piercing and nauseating pain. This morning 
it was found that there were two more openings in this 
lesion and with serum and pus oozing from each. One of 
these openings is near the center of the lesion and the other 
at about where the anterior end of the larva is situated. 
