CONTENTS 
Page 
The Role of Animals in Biomedical Research 89 
Nonhuman Primates in Biomedical Research 89 
Experimental Animals’ Contribution to Coronary Artery 
Bypass Graft Surgery 94 
Use of Multiple Species in Biomedical Research 94 
Choice of Species 98 
The Role of Animals in Behavioral Research 99 
What is Behavioral Research? 99 
Why Are Animals Used in Behavioral Research? 101 
Methods of Behavioral Research 102 
Use of Multiple Species in Behavioral Research 103 
Pain and Distress in Research Animals 103 
Animal and Nonanimal Protocols in Biomedical and 
Behavioral Research Reports 105 
Survey Findings 106 
Survey Limitations 106 
Summary and Conclusions 108 
Chapter 5 References 109 
List of Tables 
Table No. Page 
5-1. Some Uses of Nonhuman Primates in Research on Human 
Health and Disease 90 
5-2. Some Anatomical, Physiological, and Metabolic Similarities and 
Differences Between Humans and Various Laboratory Animals 97 
5-3. Classification of Research Experiments and Procedures According 
to the Degree of Pain or Distress for the Animal 105 
5-4. Classification of Published Research Protocols in 
OTA Survey of 15 Journals 106 
5-5. Percentage of Papers (Average, 1980-83) Using Animal, Nonanimal, 
and Human Subjects in 15 Biomedical and Behavioral Research Journals 
Surveyed by OTA 107 
Figure 
Figure No. Page 
5-1. Steps in Biomedical Research That Preceded Successful 
Coronary Artery Bypass Graft Surgery 95 
