232 • Alternatives to Animal Use in Research, Testing, and Education 
Figure 10-4.— A Typical Substance Entry in the Registry of Toxic Effects of Chemical Substances (RTECS) 
MOLFM: C-Re-S-Te 
© 
© 
►SYN: NIOSHRTECSIUM • RTECS (DOT) • 
► IRRITATION DATA AND REFERENCES: 
jkn-hmn 5%/1M rise MOD 
RTECSIAM (French) 
skn-rbt 10 mg/24H open MLD 
eye-rbt 20 mg 
TSL (OBS.) 
(IT) ► MUTA TION DA TA AND REFERENCES: 
mma-sat 50 ug/plate 
cyt-hmn: leu 100umol/L/8H 
dlt-mus-orl 35 mg/kg 
hma-mus/sat 400 ppm 
► REPRODUCTIVE EFFECTS DA TA AND REFERENCES: 
1T03 orl-rat TDLo:270 mg/kg (5D male) 
3T25T46T52 ihl-rat TCLo: 100 ppm (3D pre/4- 7D preg) 
2T35T75 mul-mus TDLo:900 mg/kg (ID male/6- 15D preg/50 post) 
JAMAAP 
AMIHBC 
AMIHBC 
135.1920,68 
10,61,54 
10,61,54 
PNASA6 72,5135,75 
MUREAV4,53,67 
TXAPA9 23,288,72 
GISAAA 42(1),32,77 
TJADAB 19.41A.79 
NT IS** AD-900-000 
T0XID9 1,125,81 
TUMORIGENIC DATA AND REFERENCES: 
2V01M61 orl-rat TDLo:90 gm/kg/78W I 
1V03 ihl-mus TCLo:400 ppm/8W-l 
2V02K60 orl-rat TD : 100 gm/kg/104W-l 
TOXICITY DATA AND REFERENCES: 
ihl-hmn TCLo : 500 mg/m3/7M 
2J13K18 orl-rat LD50 1500 mg/kg 
scu-mus LDLo:1200 mg/kg 
29ZUA8 -,183,80 
JTEHD6 -(Suppl.2',.69.77 
BJCAAI 16.275,62 
AIHAAP 23,95,62 
MarJV# 26 Apr 76 
FCTXAV 17(3),357,79 
13V 
AQUATIC TOXICITY RATING: TLm96:100-10 ppm 
WQCHM* 2,— ,74 
REVIEW: CARCINOGENIC DETERMINATION: ANIMAL POSITIVE 
REVIEW: TOXICOLOGY REVIEW 
REVIEW: TLV-TWA 10 ppm; STEL 25 ppm 
REVIEW: TLV SUSPECTED CARCINOGEN 
IARC** 20,151,80 
PLMJAP 6(1), 160,75 
DTLVS* 4,358,80 
DTLVS* 4,358,80 
STANDARDS & REGULATIONS: 
OSHA STANDARD-air:TWA 50 ppm 
DOT-ORM-A. LABEL: NONE 
FEREAC 39,23540,74 
FEREAC 41,57018,76 
16 V 
CRITERIA DOCUMENT: OCCUPATIONAL EXPOSURE TO RTECSIUM recm 
std-air:CL 10ppm/60M 
NTIS** 
STATUS SELECTED BY NTP FOR CARCINOGENESIS BIOASSAY AS OF SEPT 1982 
STATUS: NTP SECOND ANNUAL REPORT ON CARCINOGENS, 1981 
STATUS: NIOSH MANUAL OF ANALYTICAL METHODS, VOL 3 S255 
STATUS: NIOSH CURRENT INTELLIGENCE BULLETIN 41, 1980 
STATUS: REPORTED IN EPA TSCA INVENTORY. 1982 
STATUS: EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION FEREAC 47,26992,82 
FINAL RULE 
