App. A — Testing Guidelines • 385 
81-2 Acute dermal toxicity study 
81-3 Acute inhalation toxicity study 
81-4 Primary eye irritation study 
81-5 Primary dermal irritation study 
81-6 Dermal sensitization study 
81- 7 Acute delayed neurotoxicity of 
organophosphorous substances 
Series 82: Subchronic Testing 
82- 1 Subchronic oral toxicity (rodent and 
nonrodent): 90 day study 
82-2 Repeated dose dermal toxicity: 21 day study 
82-3 Subchronic dermal toxicity: 90 day study 
82-4 Subchronic inhalation toxicity: 90 day study 
82- 5 Subchronic neurotoxicity: 90 day study 
Series 83: Chronic and Long-Term Studies 
83- 1 Chronic toxicity studies 
83-2 Oncogenicity studies 
83-3 Teratogenicity study 
83-4 Reproductive and fertility effects 
83- 5 Combined chronic toxicity/oncogenicity 
studies 
Series 84: Mutagenicity 
84- 1 Purpose and general recommendations for 
mutagenicity testing 
84- 2 Mutagenicity tests (described in very general 
terms, with reference to the OTS guidelines) 
Series 85: Special Studies 
85- 1 Metabolism study 
85-2 Domestic animal safety testing 
Subdivision G: Product Performance 
Series 95: Efficacy of Invertebrate Control Agents 
95-1 General considerations 
95-8 Livestock, poultry, fur and wool-bearing ani- 
mal treatments 
95- 9 Treatments to control pests of humans and 
pets 
Series 96: Efficacy of Vertebrate Control Agents 
96- 1 General considerations 
96-2 Fish control agents 
96-3 Aquatic amphibian control agents 
96-4 Terrestrial amphibian and reptilian control 
agents 
96-5 Avian toxicants 
96-6 Avian repellants 
96-7 Avian frightening agents 
96-8 Mole toxicants 
96-9 Bat toxicants and repellants 
96-10 Commensal rodenticides 
96-11 Rodenticides in orchards 
96-12 Rodenticides on farm and rangelands 
96-13 Rodent fumigants 
96-14 Rodent repellants on tree seeds 
96-15 Rodent repellants on cables 
96-16 Rodent reproductive inhibitors 
96-17 Mammalian predacides 
96-18 Domestic dog and cat repellants 
96-19 Browsing animal repellants 
96-30 Methods and protocols 
Subdivision M: Biorational Pesticides 
(This subdivision duplicates many of the provisions 
of other subdivisions, and is therefore not described 
in detail.) 
Series 150: Overview, Definitions, and General 
Provisions 
Series 152: Toxicology Guidelines 
Subseries 152A: Toxicology Guidelines 
Subseries 152B: Toxicology Guidelines for 
Microbial Pest Control Agents 
Series 154: Nontarget Organism Hazard Guidelines 
Subseries 154A: Nontarget Organism Hazard 
Guidelines for Biochemical 
Agents 
Subseries 154B: Nontarget Organism Hazard 
Guidelines for Microbial Agents 
Series 157: Experimental Use Permit Guidelines 
Subdivision N: Environmental Fate 
Series 165: Accumulation Studies 
165-4 Laboratory Studies of Pesticide 
Accumulation in Fish 
165-5 Field Accumulation Studies of Aquatic 
Nontarget Organisms 
Appendix A References 
1. Organization for Economic Cooperation and Development, 
Guidelines for Testing of Chemicals, and addenda (Paris: 
1981). 
2. U.S. Environmental Protection Agency, Pesticide Assess- 
ment Guidelines (Springfield, VA: National Technical In- 
formation Service, 1984). 
3. U.S. Environmental Protection Agency , Office of Toxic Sub- 
stances Health and Environmental Effects Test Guidelines 
(Washington, DC: update October 1984). 
