APPENDIX I 
IX 
"All men exposed to the infection i.ill be* examined daily for at least 
3 weeks. You will be under the suporvisi- n of a physicicn specially 
trained to treat gonorrhea and he will bo available at all times threugh- l 
cut the study. 
"Most patients with gonorrhea can be cured 7/ithin 5 to 10 days with mod- 
ern treatment without experiencing diecoEfurt or complications. A few 
patients with gonorrhea do net respond to modern treatment methods (prob- 
ably less than 1 in IQ). These patients <fin usually be cured by the 
older methods which, however * require more time in .vhieh to get results. 
A few of the patients who are treated by those older methods develop cer- 
tain complications in the lower genital tract which, in most instances, 
are ultimately cured. In very rare instances patients treated by the 
older methods develop c- japli cations which involve the joints, the eyes, 
and other organs. 
"A very small percentage of patients treated by modern methods experience 
slight discomfort while taking the medicine. This may consist of a tired 
sensation or a slight headache, but those symptoms never become serious 
if the patient is observed daily by the physician, lever, skin rash, 
nausea and vomiting rarely occur but disappear rapidly when the treatment 
is stopped. Other reactions have boon rrp.rted v/hich involved the blood, 
joints, kidneys, liver, and nervous system, but these reactions have been, 
so rare that the possibility of thoir occurrence is extremely remote. 
"3efore we can accept you as part of cur group, it is necessary to ob- 
tain writ tan permission from you. 
" ( pl>.c& ) 
(date) 
"This is to certify that I have read, or have hud read to me, ana that 
I understand the above and foregoing statement. 
Witness ( signature) " 
******* 
SUGGESTED PERMIT A HD RELEASE 
APPLICATION FOR INCLUSION IK STUDY OH 
CHEMICAL PROPHYLAXIS FOR GONORRHEA 
"I> rt , , hereby 
(name) (age) 
voluntarily make application to 
(cooperating agencies) ~~ 
fbr inclusion in the investigation on prophylaxis for gonorrhea. 
I have read, or have had read to mo, and I understand the attached 
139 
