[ >97 1 
I have continued to ufe it as a remedy for agues' 
and intermitting diforders for five years fuccefiively 
and fuccefsfully. It hath been given 1 believe to fifty 
perfons, and never failed in the cure, except in a few 
autumual and quartan agues, with which the patients 
had been long and feverely afflicted ; thefe it reduced 
in a great degree, but did not wholly take them off; 
the patient, at the ufual time for the return of his fit, 
felt fome fmattering of his ditlemper, which the in- 
ceflant repetition of thefe powders could not conquer . 
it teemed as if their power could reacn thus far 
and no farther, and I did fuppofe that it would not 
have long continued to reach to far, and that the dis- 
temper would have foon returned with its piifiine 
violence j but I did not ftay to fee the iffue . I added 
one fifth part of the Peruvian bark to it, and with 
this final l auxiliary it totally routed its adverfary. 
It was found necefiary likewife, in one or two obfti- 
nate cafes, at other times of the year, to mix the fame 
quantity of that bark with it j but thefe were cafes 
where the patient went abroad imprudently, and 
caught cold, as a poft-chaife boy did, who, being 
almoft recovered from an inveterate tertian ague, 
would follow his bufinefs, by which means he not 
only negleded his powders, but, meeting with bad 
weather, renewed his diftemper. 
One fifth part was the largeft and indeed the only 
proportion of the quinquina made ufe of in this 
compofition, and this only upon extraordinary occa- 
fions: the patient was never prepared, either by vo- 
miting, bleeding, purging, or any medicines of a 
fimilar intention, for the reception of this baik, but 
he entered upon it abruptly and immediately, and it 
was 
