[ 23 2 ] 
CASE I. 
S I R, 
Read June 23, yl Man aged forty-two years, not 
1763. much addicted to fpirituous li- 
quors, nor too rigidly abftemious, feven months ago 
received a violent blow on the right hypochondri- 
um: foon after he was feized with the colic, and 
had a yellow fuffufion over his fkin : himfelf dated 
the aera of his misfortune from the blow. At firft 
he had a diarrhoea, but at laft became fo coftive as to 
have no regular inteflinal difcharge, but by the help 
of lenitives. He was much emaciated towards the 
end of life, his fkin was aftonilhingly yellow, and 
dry as parchment, or leather fhrivelled by the fire. 
Many medical proceffes were employed ineffectually. 
He had no confiderable pain any where. A week be- 
fore his death the left arm turned quite black. He 
had frequent haemorrhages from his nofe. On difleCtion, 
the liver was found confiderably enlarged, external- 
ly of a pale lead colour, harder and more folid than 
in a found date, but not fchirrous j internally, more 
porous and fpungy. The inner fubftance not deviat- 
ing from its natural colour, feemed to be made up 
of diftinCt fibres interfe&ing one another, with va- 
cuities between them equal in fize to the fmall cells 
of honeycombs. The duCtus cyfticus, and hepaticus, 
as well as the pori bilarii were perfectly ligamentous. 
The gall-bladder had changed its pyriform figure, 
and affeCted that of a cylinder, the fibres of which 
were 
t 
