[ 454 ] 
thefc applications have had little or no effeCt, but 
that the difeafe has given way to, and been totally 
removed by the ufe of perpetual blitters to the part 
attested ; which fhould, in mott inftances, be conti- 
nued for feveral weeks. At other times, I have 
known the Pifleleon Indicum, in Englifh called the 
Barbadoes tar, to have fo good an effcCl, by being ap- 
plied every day to the joint, for fome weeks, even 
after every other remedy had failed, as to cure fuch a 
diforder of the knee-joint, as had hitherto been judged 
defperate : in which cafe there plainly appeared to 
be an enlargement of the bones, as well as a very 
confiderable one of the integuments, and of the 
tendinous and ligamentous parts, but without any 
apparent inflammation. In this inftance there was 
no extravafated fluid could be difcover'd ; however, 
there wa& an immobility of the joint, and a confi- 
derable contraction of the hamftrings. The pain was 
extravagantly great, which the patient defcribed as 
ttiooting thro’ the ligaments of the joint, the knee- 
pan, the extremities of the thigh-bone, and thofe of 
the leg. He had a fevere fymptomatic fever, which 
had been of many weeks continuance, and was be- 
come greatly emaciated thereby. The reafon for 
my giving fo particular a relation of the circumttances 
attending this fadt proceeds from my defire of re- 
commending a tryal of the fame remedy, in the like 
cafes ; which, as far as I can judge from my own 
experience, may always be fafely done, where there is 
no degree of inflammation already formed upon the 
integuments. And I am farther induced to communi- 
cate afhort hiftory of the cafe to this Society, as it is an 
application I never faw made ufe of before, in the 
