.[ 5 * 8 ] 
where the difeafe in the natural way was epidemical 
and very mortal, and where this perfon nurfed and 
lay in bed with one, who had it, without receiving 
any new infedtion. 
To make a further tryal, the late queen Caroline 
procured half a dozen of the charity-children belong- 
ing to St. James’s paridi, who were inoculated, and 
all of them, except one (who had had the fmall- 
pox before, tho’ fhe pretended not, for the fake of 
the reward) went thro’ it with the fymptoms of a 
favourable kind of that diftemper. 
Upon thefe tryals, and feveral other in private fa- 
milies, the late queen, thenprincefs of Wales, (who 
with the king always took mod: extraordinary, exem- 
plary, prudent and wife care of the health and edu- 
cation of their children) fent for me to alk my opi- 
nion of the inoculation of the princedes. I told her 
royal highnefs, that by what appeared in the feveral 
edays, it deemed to be a method to fecure people 
from the great dangers attending that didemper in 
the natural way. That the preparations by diet, 
and necedary precautions taken, made that practice 
very dedrable ; but that not being certain of the con- 
fequences, which might happen, I would not per- 
fuade nor advife the making trials upon patients of 
fuch importance to the public. The princefs then 
alked me, if I would diduadeher from it : to which 
1 made anfwer, that I would not, in a matter fo likely 
to be of fuch advantage. Her reply was, that die 
was then refolved it diould be done, and ordered me 
to go to the late king George the drd, who had 
commanded me to wait on him upon that occadon. 
I told his majefty my opinion, that it was impodibie 
to 
