C 74 ] 
at Smyrna and Conflantinople ; allowing always, that 
the different conflitution of the air contributes very 
much to propagate the plague : for the hot air di- 
lates and renders more volatile and adtive the venem- 
ous fleams, whereas cold air contradls and mortifies 
them. The perfon having the plague may be (aid 
to have a contagious and poifonous air in his room and 
about him, while at the fame time the open air is free 
from any dangerous exhalations ; fo that I never 
was afraid to go into any large houfe, wherein a 
plaguy perfon lived, provided that he was confined to 
one room. 
The peffilential fever fhews itfelf firfl, by a chilli- 
nefs and fhiverings even in the months of July and 
Auguft, fo very like the firfl approaches of an ague, 
that it is impoffible to diflinguifh the one from the 
other at firfl fight. This cold fit is foon accompanied 
with a loathing naufea and defire of vomiting, which 
obliges the patient at lafl to difcharge a vafl quantity of 
bilious matter, with great uneafinefs and oppreffion 
in the thorax and mouth of the flomach, attended 
Sometimes with a dry cough, as in an intermitting 
fever; and even in this flage it is very difficult to dif- 
tinguiffi the one from the other. Next, the patient 
has a violent head-ach and giddinefs, with fome flight 
convulfive motions : he breathes hard ; his breath and 
fweat flink ; his eyes are ruddy, he looks frighted, 
fad, and pale ; he has an infatiable thirfl; his tongue 
is yellowiffi, with a red border; he has a total lofs of 
appetite, reflleffnefs, great inward heat, and more 
than could be expedted from the fever, which is 
fometimes pretty moderate, but grows flronger fre- 
quently towards night : the patient very often bleeds 
4 at 
