L 283 ] 
Befides the common febrile fymptoms upon the 
invafion of this difeafe, his fkin itches univerfally, 
more efpecially at the joints ; and the itching is fol- 
lowed by many little red fpots, with a fmall degree 
of fwelling : foon after his fingers become very SifF, 
hard, and painful at their ends, and at the roots of 
his nails. In 24 hours, or thereabouts, the cuticle 
begins to feparate from the cutis^ and, in ten or twelve 
days, this feparation is general from head to foot ; 
when he has many times turned the cuticle off from 
the wrifis to the fingers ends, completely like gloves ; 
and in the fame manner alfo to the ends of his toes ; 
after which his nails fhoot gradually from their roots, 
at firfl attended with exquifite pain, which abates as 
the feparation of the cuticle advances ; and the nails 
are generally thrown off by new ones in about fix 
months. 
The cuticle rifes in the palms of his hands, and foies 
of his feet, refembling bliflers, but has no fluid under 
it j and when it comes off, it leaves the fubjacent fkin 
very fenfible for a few days. Sometimes, upon catch- 
ing cold, before he has been quite free from feverifh 
fymptoms, he has had a fecond feparation of the cu- 
ticle from the cutis^ but then it is fo thin as to appear 
only like fcurf, which demonflrates the quick re- 
newal of this part. 
The figure of one of thefe gloves is feen in 
Tab. XIV. 
P o 2 XXXIX_. 
