12 
The Philippine Journal of Science 
A concise summary of my findings when the autolyzed yeast 
extract was given to human patients is as follows: 
1. About two score cases were treated; five were children 
below 2 years of age; ten were treated in hospital; all others 
were out-patients. 
2. Adults were given from 15 to 40 cubic centimeters three 
times a day. Children were given from 2 to 4 cubic centimeters 
every three hours, or six times a day. Bigger doses did not 
seem to give better results. No sign of poisoning was observed. 
3. Only acute and uncomplicated symptoms of beriberi were 
observed under treatment. Chronic nerve, muscular, or cardiac 
lesions were actually unaffected. 
5. All acute peripheral symptoms of neuritis were affected 
quickly. Marked results were noted in less than three days, 
and a week’s treatment seemed to give full relief in mild acute 
cases. Treatment was generally followed up for two weeks at 
least. 
6. Infantile-beriberi symptoms were relieved with comparative 
rapidity. CEdema yielded quickly, and nutrition improved at 
once. 
7. No special diet was prescribed. Patients were given re- 
gular hospital diets in accordance with the state of their digestion. 
8. Children receiving the extract continued to nurse at the 
mother’s breast. 
9. The effect of the autolyzed yeast extract used is similar to 
that produced by the hydrolyzed extract of rice polishings; it 
seemed weaker, however. 
