XIV, 1 Lantin: Treatment of Typhoid Fever 33 
therapeutic agent, and they have drawn others into the ranks. 
Among the leading investigators in this field, according to Gay 
and Chickening, (11) are Ardin-Delteil, Negre and Raynoud, 
Boinet, Delearde and Leborgne, Sable, Netter, Roques and Al- 
faro, Feistmantel, and Garbat. 
In this series there were ten cases treated with sensitized 
typhoid vaccine intramuscularly, and the series was treated just 
after the series of cases treated intravenously with sensitized 
vaccine. 
Table IX . — Condition of patients before treatment. 
Cases. 
Severe and toxic 3 
Severe and nontoxic 3 
Mild 4 
Total 10 
Mode of treatment . — The sensitized typhoid vaccine, as stated 
previously, was administered intramuscularly. The dosage em- 
ployed was from 250 to 1,000 millions every three or four days. 
Gay advised 800 millions every other day and Garbat 500 millions 
every five or six days. The results of this treatment upon the 
course of the disease are shown in Table X. 
Table X. — Sensitized typhoid vaccine administered intramuscularly. 
Cases. 
Days 
before 
treat- 
ment. 
Dura- 
tion of 
treat- 
ment. 
Dura- 
tion of 
disease. 
Classification by results. 
Mild. 
Severe 
and 
non- 
toxic. 
Severe 
and 
toxic. 
Total. 
Aborted . . ___ 
4 
0 
0 
4 
10 
Days. 
3 2 
Days. 
13.2 
Benefited- - . 
0 
2 
0 
2 
16 
11.0 
27.0 
Relatively unaffected . . 
0 
1 
0 
1 
11 
32.0 
43.0 
Deaths . , _ . 
3 
3 
Crisis 
1 
Lysis 
3 
Average--, . 
27.7 
Thus, it may be seen that there were four abortive cases, all 
observed in the beginning of the second week, and ail of them 
mild, in which the average duration of the disease was 13.2 days ; 
two benefited cases, during the third week, both of the. severe 
and nontoxic type, with twenty-seven days as the average dura- 
tion of the disease; and one relatively unaffected case of the 
same type as the benefited cases, with forty-three days as the 
average duration of the disease. The total average duration of 
