42 
The Philippine Journal of Science 
1919 
was delirious and semiconscious, from the time of admission up 
to death. Autopsy findings of these two cases are as follows: 
Autopsy findings {milk injection) . 
File No. 2662: S. L. 
Anatomic diagnosis: Acute ulcerative enteritis with haemorrhage 
(typhoid) ; acute splenitis and lymphadenitis (mesenteric) ; acute 
cardiac dilatation ; acute parenchymatous degeneration of the viscera. 
File No. 100: M. C. ^ 
Anatomic diagnosis: Ulcerative enteritis (healing typhoid); intestinal 
haemorrhage; subacute splenitis; dilatation of the heart; broncho- 
pneumonia (hypostatic) ; suppurative nephritis; acute myocarditis; 
parenchymatous degeneration of the liver; fibroma, left kidney. 
The above necropsy records show that the patients died of 
complications. 
COLLOIDAL GOLD INJECTED INTRAVENOUSLY 
Colloidal gold, or colibiase as it is sometimes called, has been 
used extensively by French clinicians for a variety of infectious 
diseases, such as typhoid fever. Among the leading clinicians 
following this method, according to Gay, (9) are: Letulle and 
Mage (25) in 1914, Gay in 1915, Barachon in 1916, Labbe and 
Mausand in 1916, and Delbet in 1916. 
A series of fifteen patients was treated intravenously with 
colloidal gold in connection with this study. This treatment 
was carried out when the morbidity of the epidemic was going 
down. The clinical grouping of the cases is given in Table XX. 
Table XX . — Condition of patients. 
Cases. 
Severe and toxic 5 
Severe and nontoxic 7 
Mild 3 
Total 15 
Dosage . — The dose employed by Letulle and Mage (25) in con- 
nection with their forty -two cases ranged from.l to 2.5 cubic 
centimeters intravenously, 1 cubic centimeter for mild cases and 
2.5 cubic centimeters for severe cases. The dose administered 
in my series was from 0.5 to 5 cubic centimeters intravenously, 
depending upon the severity of the case. In the majority of 
instances, 2 to 3 cubic centimeters was the initial dose. 
The results of the treatment are shown in Table XXI. 
