[ 47 ° 3 
the outfides of his legs, from the knees to the ancles, 
as well as in blotches upon other parts of his body. 
It had the appearance of a dry branny fcab or fcurf, 
which every night fell off, more or lefs, in fcales, as 
is ufual in leprous cafes. At times it puflied out 
more than ufual, and thickened the integuments of 
the limbs confiderably, after which the feparation of 
fealss would become very abundant. 
For feveral years pafb he had been trying a variety 
of things commonly recommended in fuch cafes, 
particularly the quack medicine known by the name 
of Maredani’s Drops, which he continued for near 
a twelvemonth, without finding the lead: fenfible re- 
lief : alio an electuary of Flos fulphuris and Cremor 
tartari, which he had perfevered in for near three 
years, without finding any other alteration, than 
that of its preventing coflivenefs, to which he was 
habitually fubjeft. 
In the winter 1770, this diforder increafed upon 
him very rapidly, without being able to affign any 
reafon, from any accident that had happened to him, 
or from any irregularity of his own in point of regi- 
men, in which he was always very exa£I. At this 
time, befides the farther fpreading of the eruption 
itfelf, the integuments of the legs thickened very 
much, and the limbs fwelled to fuch a degree, as 
to render him unable to walk. The quantity of 
branny fcurf and fcales thrown off, at this time, was 
very great ; he fays “ handfuls might have been 
taken out of his bed every morning.” 
In this unhappy fituation, even loathfome to him- 
felf, it was recommended to him to take the juice of 
water parfnep, in the quantity of one common table- 
fpoonful 
