BACILLI SIMILAR TO THE DlPHTIlERtA BACILLUS 439 
a similar pleoniorpliic bacillus from several cases of Hodgkin's disease.^ 
Initial cultures were obtained upon Dorset's egg medium. Subse- 
quent development upon ordinary media gave the following cultural 
reactions: gelatin not liquefied; little or no change in litmus milk; 
an adherent growth in l)r()th tubes with the gradual accumulation of 
a slimy sediment. The colonies upon serum and agar are not charac- 
teristic. 
Fig. 62.— Pseudodiphtheria bacilli. (Park.) 
Morphologically the organism is variable in shape. Bacillary 
forms predominate in young cultures, but the bacilli exJiibit a marked 
tendency toward coccoid elements after prolonged cultivation. 
The etiological relationship of the organism,'- which received the 
name Corynebacterium hodgkini, to Hodgkin's disease is as yet unde- 
termined, but vaccines injected into several typical cases are said to 
have caused a definite recession in the size of the enlarged glands. The 
permanence of this recession must await confirmation. 
Bunting and Yates'^ injected their organism into monkeys, and a 
chronic lymphadenitis with an increased mononuclear and eosinophile 
count resulted. A polymorphonuclear leukocytosis was not observed. 
They conclude that the anatomical lesions were very similar to those 
observed in the early stages of Hodgkin's disease in man. 
1 Fox: Arch. Int. Med., 1915, 16, 465. 
2 See excellent rt'sume by Bloomfield (Arch. Int. Med., 1915, 16, 197). 
' Jour. Am. Med. Assn., 1913, 61, 1S03; ibid., 1914, 62, 516. 
