24 CASE OF ACUTE GLANDERS OF SPONTANEOUS ORIGIN. 
H ospital St. Antoine, still is the spontaneous development of the • 
disease looked upon as peculiar to Solipedes alone. Although 
men be submitted to the same influences as produce glanders 
and farcy in horses, yet is there no fact to prove that they 
become affected by such causes. And notwithstanding there 
are some scattered facts of the kind on record, still have they 
not found attention, either from their being ill-established, or 
from the circumstance of their being considered without the 
pale of possibility. 
M. Teissier proposes to sho'w, in the face of these con- 
clusions, 1st. That the case in question is fairly one of 
glanders ; and 2dly. That the disease was not communicated 
either by inoculation or infection. 
A woman, named Adelaide James, forty-seven years of 
age, was admitted into the Hotel-Dieu on the 8th of June, 
1851, married, but for two years has not lived with her hus- 
band. She is a silk-worker, and lives in apartments open 
and well ventilated, leading a sedentary life. She has had 
no communication with horses, or coachmen, or grooms, or 
cavalry soldiers ; in fact, has never touched anything likely 
to infect her with glanders. In 1849 she contracted syphilis, 
of which she got well in a couple of months. 
On the 30th of May, 1851, having, as she said, exposed 
herself to a current of air whilst in a perspiration, she had 
a shivering fit which lasted four hours, accompanied with 
weakness, cephalalgia, anorexia, and more than all, sharp 
pains in her joints. On the fourth day afterwards, reac- 
tion having become established, a white pustule with a 
red areola came upon her right leg. On the fifth, her two 
feet became attacked with cedematous erysipelas, wdiile upon 
her arms as well as legs suddenly appeared tumours, with or 
without change of colour in the skin, consisting of hard and 
more or less painful nodosities ; of which one, soon after, 
suppurated. This happened before her admission into the 
hospital. Afterwards, her legs became oedematous, and pre- 
sented diffuse erysipelatous patches. Tumours, some hard 
and painful, with or without inflammation, continue to arise 
upon her arms and legs, wdiile others become abscesses and 
fluctuate. Fever, with slight occasional delirium. Fresh 
abscesses form, wdiilst some of the old ones appear to be ab- 
sorbed; and the ulcerations upon the leg are some of them 
becoming gangrenous, and she cannot bear the slightest 
pressure upon it. 
Here w r as a case of low fever wdth tendency to break out 
into manifold small abscesses, with erysipelatous inflam- 
mation, and they put on the aspect of varioliform pustules. 
