PLEURO-PNEUMONIA IN CATTLE. 
415 
4. The blood of the same cow. 
5. The blood of a healthy ox under epizootic influence for 
five months. 
6. The blood of a healthy ox not under epizootic influence. 
7. Parts of the liver and of the large right pectoral muscle 
of the abdomen from the diseased cow. 
In none of these matters did I find the small corpuscles 
with molecular motion, while I have constantly met with 
them in the lungs and in the intestinal tubercles of animals 
affected with pleuro-pneumonia. That, then, is the principal 
seat of the disease. Are these corpuscles primitive, or con- 
sequent on the disease ? This question cannot be decided 
now ; I only wish here to verify their presence in pleuro- 
pneumonia. 
1 examined with the microscope parts of the derma of the 
external skin (and which I still have in alcohol) from one of 
the oxen that died in consequence of the inoculation. I 
found there the same microscopical elements, and the same 
chemical characters as in the lungs of the animals diseased 
with pneumonia. 
To make certain of my observations, and to have them 
tested, I sent, on the 12th February, 1852, a portion of the 
skin and of the underlying tissue from the animal that died 
the previous evening in consequence of the inoculation, to 
M. Vankempen, a distinguished anatomo-pathologist, for 
examination, and here is what the learned Professor wrote to 
me : 
u I have just examined the specimens you forwarded to 
me, and this is the result: I recognised in them small 
corpuscles endowed with a particular molecular motion; they 
are of very various sizes — some are punctiform, others show 
a very distinct central light — and they resist the action of 
acetic acid. In the same piece of skin I met with assem- 
blages of granulous kernels (see Fig. 3, p. 8) in which there 
is a small nucleus. These kernels resist the action of acetic 
acid, and that is the precise character of kernels. It is 
absolutely as if there had been an abundant exsudation in 
the derma.” 
Be pleased to observe, Sir, that M. Vankempen was at 
the time entirely ignorant of the inoculations that I was 
practising, and that he did not know of what disease the 
animal had died. 
The physical characters, the microscopical examinations, 
and the chemical analysis of the part where the inoculation 
was made, prove that the local artificial disorder produced 
by the inoculation has the greatest resemblance to the com' 
