INOCULATION FOR PLEURO-PNEUMONIA IN CATTLE. 449 
not-inoculated animals. It is, however, remarkable that it has not 
occurred with No. 25,* although the regular period is already past. 
“ 8th. The unproductive effects on Nos. 5 and 12, consequent probably 
on abortion, cannot, as long as these two cases remain isolated, be ascribed 
to inoculation; more particularly as, with Nos. 19, 21, and 23, where 
considerable action prevailed, it did not occur. 
“ 9th. Although it cannot with perfect certainty be determined whether 
premature calving of the cow (No. 10) near her time of calving, and 
the symptoms observed on that cow and subsequently on the calf, as 
well as the premature calving of No. 14, are attributable to the previous 
inoculation, it would not be advisable in advanced stages of bearing to 
apply it. 
“ 10th. Although abortion on the first appearance of the disease fre- 
quently occurs, it is worthy of remark that it never occurred with 
animals where action was so severe as to occasion death (as in case 
No. 9) ; so that, if inoculation exercises influence on pregnancy, it pro- 
bably only does so in the last stage. 
“ lltli. The supposition noticed in the first report, that the commence- 
ment of the disease after inoculation is only to be ascribed to its having 
been in existence at the time of inoculation (of which nevertheless not 
one single appearance has been observed), obtains greater probability 
from the present experiments. 
“ 12th. The assertion that animals having once had the pulmonary dis- 
ease and been cured, never, or at least rarely, take the disease for the 
second time, and that inoculation in such cases remains inoperative, is 
confirmed in case No. 16, on whom inoculation twice repeated produced 
no effect. And finally : — 
“ 13th. Although the present trials prove in a remarkable degree that 
inoculation possesses the power, at least temporarily, to prevent infection, 
it remains uncertain how far disposition for the disease is completely, or 
only for a longer period, destroyed. 
“ From the nature of the subject a considerable time must elapse be- 
fore any positive conclusion can be acquired on this point. 
“ The Committee has thus endeavoured to make your Excellency^ 
acquainted, as circumstantially and accurately as possible, with the result 
of its investigation. 
“ It has entered into extensive detail in order as far as possible to state 
every particular relative to inoculation and its consequences, with a view 
thereby, and by a faithful detail of the progress of its inquiries, to re- 
move from the minds of our cattle proprietors the unfavorable impres- 
sion produced by the rash, or at all events premature, judgment of 
veterinary practitioners in a neighbouring country, which has been 
noticed in several newspapers ; neither does the Committee, from the 
result of acquired experience, hesitate to recommend inoculation, under 
prudent treatment, in every case where pulmonary disease has broken 
out in a herd of cattle, or in the neighbourhood. 
(Signed) “ P. H. J. Wellenbergh. I. Jennes. 
It. J. C. Panders. F. C. IIekmeyer. 
G. Wit. J. P. E. Van Laer. 
“ Utrecht ; Dec. 28, 1852.” 
• This and all subsequent numbers named in the extract have reference to 
animals alluded to in other parts of the Report of the Commission where the 
details of each case are given. 
f The Report is addressed to his Excellency the Minister of the Home De- 
partment. 
xxvi. 59 
