GLANDERS IN THE HUMAN SUBJECT. 207 
frequent, and very feeble, and his tongue dry. After this, we 
attempted nothing more than the stimulating treatment, by in- 
creased doses of wine, carbonate of ammonia, and two doses of 
quinine, which had no obvious effect, and he died at four o’clock 
next morning, having been only thirty-six hours in the house. 
If there could be any doubt as to the nature of this case 
during life, I think there could be none when it was found, on 
examination of the body, that within the larynx there was a 
pustule, similar to those on the skin, a little above the chordae 
vocales on the right side, and several smaller pustules of the 
same kind in the trachea : the bronchi contained muco-purulent 
matter of little tenacity, these membranes being moderately in- 
jected ; the lungs presented several ecchymosed circular patches, 
scattered through various parts of their substance, each of which 
contained a central yellow granular deposit, gradually breaking 
down into pus. These, when near the surface, had the appear- 
ance of circular pustules, surrounded by a border of ecchymosis, 
very similar to those on the skin. On opening the nasal cavi- 
ties, a line of small circular ulcerations was observed between 
the inferior and middle turbinated bone on the left side, which 
were infiltrated with pus. There was no such appearances on 
the opposite side ; nor was any disease found in the liver, nor 
in any of the veins or lymphatics which were examined. 
We could not ascertain anything farther as to the history of 
this patient, than that he had been employed, up to the time of 
his illness, in a stable, in which a veterinary surgeon, who at- 
tended the examination of the body, said he knew there had 
been several cases of glanders. I learnt from Mr. Dick, Pro- 
fessor of Veterinary Surgery, that he was aware of there having 
been cases of glanders recently in some of the stables for hackney 
coach horses, although he had not himself seen any. 
I can say with certainty, that the appearances on the face, 
nose, and eye, here were exactly similar to those I saw in the 
one case, likewise fatal, some years ago in the hospital, which 
was traced to infection from a stable some miles from town 
(where there were, undoubtedly, glandered horses), excepting 
only in this, that in that case the inflammation on the face went 
to gangrene, which I never saw in erysipelas of that part. In 
this case, likewise, from the state of the general system, it is 
very likely that gangrene would have ensued, if the typhoid 
fever had not been so early fatal. The appearances on the skin 
were manifestly similar to those of the pustule maligne of the 
French authors, and of the glanders in human subjects, de- 
scribed by Dr. Elliotson, in their early stage. 
What is most deserving of notice here, is the confirmation 
thus given of the principle, which former observations seem in* 
