ON INOCULATION OP PLEURO-PNEUMONIA. 405 
At the expiration of 38, 41, 44, and 48 days of cohabitation, 
peripneumonia declared itself in succession in 4 or 5 un- 
inoculated beasts belonging to the herd of experiment, and 
all four succumbed to the disease. 
The inoculated animals presented, up to the 28th Dec., 
the date of the Report of the Commission, all the signs of 
perfect health. 
“Not one of these cows,” says the reporter, “during their 
sojourn of three months in the infected stable, has shown the 
slightest sign of disease which tended to evince, even in the 
feeblest manner, the approach of peripneumonia. Everything, 
in fact, went to convince us, by the excellent condition of the 
cattle — their thriving aspect, and the brightness of their 
coats — to the contrary. 
These experiments furnish a remarkable proof, according 
to the Netherlands Commission, that we do not deny to 
inoculation, a power, at least temporary, of preservation 
against the contagion of pleuro-pneumonia : nevertheless, it 
remains uncertain in regard to it, up to what point the pre- 
disposition to take the disease is lost, whether altogether, or 
for a limited term. 
2. Experiments of the Belgic Scientific Commission. 
Desirous of disencumbering inoculation of numerous ac- 
cessory questions which the practice is apt to raise, the 
Commission adopted in its experiments the following simple 
programme : 
1 . To purchase healthy beasts ; to observe them for a cer- 
tain time, in order to feel assured of the integrity of the 
pulmonary organs. 
2. To beg M. Willems to inoculate them. 
3. To admit as preserved only those in whom this physician 
should be able to recognise specific inflammation, excited by 
prosperous inoculation ; and so pronounce in the enjoyment 
of immunity. 
4. To cause such beasts to cohabit with animals tainted 
with exudative pleuro-pneumonia, placing the same in con- 
ditions identical with non-inoculated animals. 
In consequence of this programme, a first convoy of eight 
cows and Ardenne heifers were bought in localities free from 
pleuro-pneumonia, and inoculated by M. Willems on the 16th 
Aug. 1852. The l6th Sept, following, six of them presented 
all the symptoms of a successful inoculation. 
The same day, M. Willems inoculated eight other beasts, 
purchased on account of the Commission at Tirlemont fair, 
xxvii. 53 
