CONTAGION OF GLANDERS TO MAN. 673 
of the pericardium, and even of the substance of the heart, 
by divers foreign bodies (such as pins, needles, &c.), coming 
from the interior of the reticulum and rumen.* 
The general symptoms are anxiety, shivering, coldness 
skin, want of appetite, disordered digestion, and cessation of 
rumination, such as may be remarked in almost all the 
grave affections of bovine animals ; however, I ought to add, 
it is only in pleuritis and pericarditis that I have observed 
coldness of the skin, mouth, and horns, to be so intense, and 
that profound anxiety to be present which is the sure indi- 
cation of a severe attack of the organism. 
To resume, the venous pulse, the engorgement of the 
jugulars, the intense force and pulsations of the heart, pain 
in the cardial regions, show the differences between peri- 
carditis and pleuritis. 
At the periods of increase and confirmation, the firmness 
and size of the external jugulars, the complete absence of 
pulsation of the heart, the appearance of swelling under the 
jaw, and in front of the breast, the metallic tinkle and pain 
on percussion of the walls of the thorax upon a level with 
the pericardium, are pathognomonic symptoms of pericarditis. 
Lastly, when with these symptoms come to be united 
diminution or almost cessation of the respiratory murmur in 
the lower half of the chest, while there is augmentation of 
the murmur in the upper half of the cavity, the absence of 
pain on the percussion of the superior half, the double ex- 
piration, with contortion of the ribs as in hydrothorax, we 
maybe certain that a considerable quantity of fluid is present 
within the pericardium. Rec . de Med. Vet. de Sept., 1854. 
CONTAGION OF GLANDERS TO MAN. 
Veterinary journals have already published several ex- 
amples (unfortunately but too many) of the contagion of 
glanders of animals to man. Researches in pathological 
anatomy have been by some medical men directed to this 
point, and it has been ascertained that the transmission of 
this terrible disease of solipedes to man, has turned out a sad 
reality, and augmented the nosological catalogue of human 
kind which had already calamities enough assailing them. 
* Some facts seem to make it appear to me that pericardites, which are 
owing to these traumatic lesions of the heart and its envelopes, ordinarily 
appear of the sub-inflammatory type. 
