CONTAGION OF GLANDERS TO MAN. 67 5 
itself equally on the right side ; the gland was much more 
swollen, lumpy, and adherent to the bone, and is painful; 
appetite diminishes ; emaciation makes notable progress, and 
the septum nasi presents numerous pustules, and in several 
places ulcerations ; indeed, in the second patient, agglomerated 
and re-united in a manner to form one sheet of ulceration, 
with ragged borders and a dirty uneven base. The testicular 
organs in both animals remained unaffected. 
From this moment there was no longer any doubt : both 
horses were immediately destroyed. 
For the last fortnight these horses had been treated by the 
proprietor himself, who in the course of that time contracted 
the glanders in spite of all the precautions I had strongly 
urged him to take : not doubting but that he exposed himself 
to great risks. Notwithstanding, one could not positively 
assert the channel through which contagion had taken place ; 
it was easy to suppose what the contagious agent was, and 
how the glandered virus had operated. 
Towards the 9th of March this unfortunate proprietor, a 
man of middle age, robust health, and in possession of a tem- 
perament which up to that time had resisted all sorts of 
fatigues, exhibited on his right arm, a little above the elbow- 
joint, a pretty voluminous tumour, sensitive to the feel, hav- 
ing the appearance of purulent phlegmon, and yet offering all 
the characters of a recent inflammatory swelling. Sharp 
attack of fever, considerable depression, sinking in some mea- 
sure of the vital functions ; a notable alteration in his features 
take place with this purulent collection. After several emol- 
lient applications, the tumour was opened, and gave issue to 
abundance of pus of laudable character, (though what 
rather astonished the doctor in attendance) was the sudden 
and marked separation of the lips of the wound which after- 
wards became everted and converted into a sort of ulcer, the 
cicatrization of which, nevertheless, took place with sufficient 
promptitude. Some days after similar swellings rose, first on 
the limbs, then on the arms; but this time, after having ex- 
hibited some slight inflammatory symptoms, they disappeared 
without leaving any traces of their existence. 
At length, his face partook of the general alterations : a 
green glandered discharge issues in abundance from the nos- 
trils and sticks about them ; the face becomes swollen up to 
a degree ; pustules at first, and afterwards veritable chancres 
are developed around and in front of the nose ; he becomes more 
and more emaciated, and on the 19th or 20th of March falls a 
victim to the destructive disease, without having suffered any 
very violent pain from it. 
