EFFECTS OF MEDICINE ON HORSES. 
109 
means have proved abortive. There is, unfortunately, an objection 
to its long or continued use, which, by some medical men, is re- 
garded of so serious a nature that they hardly dare resort to it at 
all — certainly not without forewarning their patients; and this is, 
that it has in several instances been known, after a long or con- 
tinued exhibition, to cause discolouration — a sort of blueness — of 
the patient’s skin, from some change it has apparently worked in 
the inter-cuticular tissue, the rete mucosum. I do not know that 
we have any reason to apprehend such discolourations being pro- 
duced on our patients, or that it would signify much if such a 
thing were to happen. 1 have given the silver to one horse in 
considerable doses, and have persevered in it : with what effect 
will best appear from the case itself. 
In the year 1818, a bay horse, five years old, was taken up 
from the strawyard in good condition in consequence of having 
the submaxillary glands on both sides in a state of tumefaction, 
and shewing ulceration of the membrane upon the septum in the 
off nostril. The case being regarded as one of pure sub-acute 
glanders, without any disturbance of the general health or appetite 
or spirits, and, having been desirous for some time back to give 
the lunar caustic a trial as an internal medicine, he was on the next 
day, the 23d of February, ordered to take argent, nitrat. gr. v, 
cum farina lini et theriac. morning and evening. 
February 2 1th . — Double the dose morning and evening. 
2 5th . — The near nostril has become ulcerated in a similar man- 
ner to the off. Let him take a scruple of the silver morning and 
evening. 
2 6th . — Has not eaten so well as usual. Continue medicine. 
21th . — Eats scarcely any hay, and his pulse has become accele- 
rated. The excretions are regular. Continue the balls, and touch 
the ulcers with a weak solution of bi-chloride of mercury. 
28th . — Appetite still indifferent. The nasal flux has a healthier 
aspect, and the ulcers have lost much of their foul character. 
Augment the dose to 9iss morning and evening. 
29th . — If any difference, his appetite has rather improved. Take 
9ij morning and evening, and have the ulcers dressed as before 
with the bichloride in a weak solution. 
March 1st . — Failed in eating all his corn last night, but ate 
some hay : continued as yesterday. 
2d . — He has almost recovered his wonted appetite, and his ex- 
cretions remain of a normal character. The submaxillary tume- 
factions, from having been tense and fixed, have become loose and 
moveable. Let him take a drachm twice a-day. 
3 d . — His appetite is quite restored. The ulceration in the nose 
VOL. XVII. P 
