EFFECTS OF MEDICINE ON HORSES. 
511 
There has also been for the last day or two some appearances of 
discharge issuing from the other nostril ; and this morning the flux 
is as abundant from one side as the other, and its oflensiveness 
continues. 
August 4th . — Has failed in his appetite, and in the evening 
threw out blood again from his nose. 
5th . — This morning, early, I was called to him for being “griped.” 
1 found him expressing a great deal of anxiety and pain, pawing 
occasionally, and from time to time casting woful looks at his 
flank. I ordered him a sedative (laudanum) draught ; and had it 
repeated at intervals of two hours. It relieved him temporarily. 
At half past eleven o’clock, A.M., however, he died. 
Post-mortem . — More marked signs of inflammation in the mu- 
cous linings of the intestines than in that of the stomach. Lungs 
in a state of tuberculous disease throughout their substance. The 
near proved the only side of the head affected with the disease, 
which, from the first, was evidently glanders. The near frontal 
sinus exhibited a great deal of ulceration, and contained a foetid 
purulent matter of the same character as what had run from the 
nose. Within the maxillary sinus was found a considerable effu- 
sion of lymph floating in the contained purulent matter. From 
such an inveterate case as this I could not have expected any good 
result, even had not the medicine proved fatal ; and, therefore, 1 
still entertained the same desire to give the barytes in its pure form 
a fair trial. 
CASE VIII. — In order that the experiment might be of a kind 
the least subject to objection, a horse, healthy in every respect 
save lameness from navicular disease, and but seven years old, 
was made the subject of it. He was accordingly inoculated for 
glanders with matter which I had taken great pains myself to 
procure from Cow Cross, taking it from a horse standing for 
slaughter in the yard, whose disease — glanders — appeared of the 
most acute and malignant description. The inoculation was per- 
formed inside the near nostril on the lltli of September 1818. 
On the 14th there was some oozing from the nostril, and the sub- 
maxillary gland upon the same side was swollen. On the 15th, 
ulceration appeared upon the near side of the septum nasi , and 
there was more discharge. 
1 5th . — There now exist two large unhealthy-looking ulcerations 
upon the inferior portion of the septum nasi, accompanied with a 
flux confined to that (the near) side of muco-purulent matter, ad- 
hering in places about the external naves. The gland has increased 
in magnitude since yesterday ; and there has risen up a cord of 
swollen lymphatics, about as large as one’s wrist, running from the 
gland along the submaxillary space. Let him commence taking 
