514 
EFFECTS OF MEDICINE ON HORSES. 
10/A. — Having received a fresh supply of the caustic barytes, 
half-a-drachin is prescribed to be given morning and evening. 
Vdth. — Since the 12th, the drachm dose has been repeated in 
the evening. To-day the doses are doubled. The ulcerations one 
day appear cleaner, another almost as foul as ever — the limb is re- 
maining much in statu quo. 
23 d . — The dose this morning consisted of the last four drachms 
of our stock of barytes. No sensible effect has been taken by the 
medicine ; nor has it proved anywise beneficial as concerns the 
disease. Here, therefore, our experiment with the pure barytes 
may be said to end. 
Not knowing what to do with the mare, confirmedly glandered 
as she is — not liking to send her away for slaughter — I determined 
on destroying her, if possible, with some carbonate of barytes I still 
had in my pharmacy. 
24 th. — Accordingly, I commenced giving her two drachms of 
the carbonate this day, repeating the dose in the evening. 
2 6th. — Three drachms morning and evening. 
27 th. — Four drachms morning and evening — Disease spreading 
within the nose. 
28 th. — Five drachms, morning and evening. 
29 thy 30 th — Six drachms, morning and evening. 
31^A — One ounce of the carbonate twice a-day : her appetite 
continues good. 
Aug. 1st . — Nine drachms, morning and evening. 
2 d . — Ten drachms, morning and evening. She falls away, 1 
think, in her condition; yet she feeds and looks well. 
8 th. — A drachm has been added daily to every dose of her 
medicine. She has seemed all along unaffected by it. Being 
forced to go to London, and not returning until the 10th of the 
month, I found she had died quite suddenly the day before. 
Post-mortem . — The disease proved the genuine chronic form of 
glanders : the membrane lining the sinuses of the head and nasal 
chambers exhibited the true miliary ulceration. There also existed 
ulceration of the cartilages of the larynx. The lungs contained 
tubercles. 
