GLANDERS. 
523 
DISCHARGE FROM THE NOSE, though the symptom 
which commonly first attracts notice, is not the first in the order of 
appearance of the local symptoms, it being often, I believe generally, 
preceded by the tumefaction of the glands underneath the throat. 
At its commencement, the discharge is scanty and limpid, amounting 
to nothing beyond a little aqueous or serous fluid, trickling or drop- 
ping, commonly from one nostril only, but without intermission. 
The next day, or the day after, this watery discharge mostly 
appears streaked or intermingled with ropes of mucus; and in a 
day or two after it will probably have become altogether mucous 
in its nature, and now glairy in its aspect, after which it gradually 
assumes a tinge of yellow, from the admixture with the mucus of 
albuminous matters, the aqueous discharge now diminishing, but 
not altogether ceasing. From this, which may be regarded as the 
incipient or first stage of glanders , the ordinary course of the 
disease is into 
The Second or Ulcerative Stage. From being aqueous 
or aqueo-mucous, with little or no show of purulent matter, the 
discharge by degrees acquires consistence, turns of a straw colour, 
exhibits true purulent characters, and soon flows in abundance, 
there remaining, however, still more or less aqueous stream mingled 
along with it. In time, this augmented flux, shewing less of the 
aqueous admixture, becomes thicker, less disposed to run off, 
acquires tenacity, and begins to cling about the hairs fringing the 
nostrils. At length, it becomes converted into a truly viscous 
flux, possessing glutinous properties of that remarkable kind that, 
like birdlime or glue, it sticks, firmly adheres to the hair of the 
nostril, collecting and concreting within the cornu or fold of the 
ala nasi , and clogging, and more or less obstructing, the aperture, 
and in this manner occasioning impediment to the breathing, 
generating a noise in the passage of the air very similar to that 
called the mucous or bronchial rale, and which to the ear of the 
experienced practitioner is a sound so peculiarly characteristic of 
the state the patient is in, that, the moment he hears it, he too 
well knows the nature of the case he is about to inspect. Indeed, 
with this glutinous flux in any considerable quantity, such is 
the foul state outwardly and the obstructed condition inwardly of 
the nasal passages, in consequence of the adhesion and retention 
of the discharges, that when even but one nostril is affected the 
inconvenience caused to respiration is much felt ; when both, how- 
ever, are in the same foul and obstructed condition, there exists, at 
the times that the accumulation of matter becomes great, danger even 
of suffocation. Also now, or before this, according to the source 
and nature of the discharges, will be observed, what was not per- 
ceptible in the first stage nor perhaps in the beginning of the 
