GLANDERS. 
583 
inflammation ; the submaxillary gland of the same side was also swollen and 
tender on pressure. On the sixth day a foul ulcer appeared upon the inocu- 
lated part. On the eighth there came discharge from both nostrils ; and the 
ass had fallen very lame in the near fore leg, seemingly from an attack (as 
yet concealed) of farcy. Ninth day , the animal commenced heaving at the 
flanks, and appeared altogether very ill, continually lying down, &c. Three 
pints of blood were drawn ; this, however, was no sooner done than he became 
faint from its loss, and staggered, and died about five minutes afterwards. 
Examination of the head shewed the Schneiderian membrane, on both sides, 
reddened and thickened in substance, its surface studded with small white 
tubercles, which, in a short time, would have turned to ulcerations; likewise 
the nasal meatus were filled with sero-mucous discharges. 
No question, I should imagine, can arise, that, in the case of the 
ass just related, glanders and farcy also were produced by inocula- 
tion. The same fact stands likewise proved in a case related 
in the late Mr. Field’s “ Records*.” Again, we may adduce, as 
confirmatory" evidence — if any be wanting — 
The Compte-Rendu of the Veterinary School at 
Alfort for 1839-40. MM. Renault and Bouley have prosecuted 
their researches into the nature and symptoms of glanders, with 
especial direction of them to its contagious property, to which in- 
creasing interest has been given since the disease — in so many 
instances — has proved communicable to the human subject; and 
they have arrived at the conclusion that acute glanders is contagi- 
ous by inoculation from horse to horse. In the animals they have 
inoculated, without a single exception the infection of glanders has 
made its appearance from the third to the fifth day. 
Standing, however, as the fact of propagation through inocula- 
tion does upon the ground of undeniable proof, yet is it also a fact 
with which those in the habit of practising inoculation are likewise 
well acquainted, that it is by no means certain that the disease 
follows the application of the virus: a good deal of fastidiousness 
or predilection is often manifested on the part of the inoculated 
subject which we are unable to account for ; and this has led some 
into the error that glanders was not at all or hardly producible in 
any such manner, and others into the belief that the chances of 
production were so small as scarcely to render such a result pro- 
bable. It is evident the success of inoculation must depend upon 
two conditions : — The condition of the animal from which the 
matter is taken to communicate the disease, and the condition of 
the one to whom the matter is applied to receive it ; and that, 
supposing either of these conditions fail, no result can follow. In 
the case of the ass but just given, it would appear that the horses 
from which the matter used in the two first inoculations was ob- 
tained, were, if glandered at all, but chronically so ; whereas the 
* Posthumous Extracts. 
