6 84 
EFFECTS OF MEDICINE ON HOUSES. 
11 th. — He has refused his corn ; so give the ball but twice. 
12th. — During the past night he has eaten scarcely any thing, 
according to the man’s report : this morning, however, he appears 
to have regained his appetite. Reduce the dose to half an ounce, 
and let him take it twice to-day. At night his pulse had risen to 
55, and was beating with considerable force : there was also some 
increase of respiration. 
13th. — His dung falls en masse , and his appetite is delicate. 
Reduce the dose to two drachms twice a-day. 
14^A. — Diarrhoea has set in, and his appetite has failed, and his 
pulse is 60. Discontinue the medicine. 
15th. — His fever has abated, and he has much recovered his 
appetite and spirits. The purgation has also ceased. Let him 
take, morning and evening, 3ij of the binoxide in combination with 
a scruple of opium, and rub some infus. lyttse upon his tume- 
fied glands under the throat. 
17th. — This prescription seems to agree very well with him. 
But the ulceration within the nose has sadly spread over and 
eroded the membrane : indeed, in places the septal cartilage 
is laid bare through it. An injection of a solution of bichloride of 
mercury has been used, and seems to have the effect of smoothing 
down the sharp jagged edges of the ulcers. 
18th. — His nose has taken to swell, seemingly in consequence 
of the injection. Let a fomentation be used to it. 
19th. — He has quite recovered his appetite, but in point of dis- 
ease is growing worse daily. Let him take the two drachms twice 
a-day, and have his nose syringed with a weak solution of sulphate 
of copper. 
22 d. — Increase his dose to three drachms twice a-dav. Ulcera- 
tion has appeared in the left nostril, and the correspondent lymph- 
atic gland is swollen. 
24^A. — Give five drachms of manganese twice a-day. Upon the 
off side the septal cartilage is laid quite bare from ulceration, and on 
the near side the membrane is rapidly being consumed. On both 
sides exist considerable enlargements of the submaxillary glands. 
It not being thought worth while to push the medicine further, 
the horse was shot. 
On the 7th of March of the same year (1813) a horse was ad- 
mitted into the infirmary for an attack of periodic ophthalmia in 
the near eye. The eye, it appears, has been “ w r eak” for three or 
four days. At present the lids are closed, the light being too much 
to be borne ; and when they are separated by force, the cornea is 
found too muddy to admit of any observation of the state of the in- 
ternal parts. Some blood was drawn from the angular vein, and 
half an ounce of the binoxide of manganese given twice a-day, 
nothing being used to the eye. 
