704 
THE HISTORY OF GLANDERS. 
tempted to bring on an inflammation upon the same membrane by 
a corrosive injection ; and, when the injection was only made on 
one side, the maxillary lymphatic glands were swelled on the same 
side, and that nostril only produced the discharge. But, on the 
other hand, when both nostrils were injected, these symptoms ap- 
peared on both sides.” — “ The first Memoir presented by Sieur 
Lafosse was confined to a bare description of the disease, and only 
a proposal of a method of cure by way of project ; but, in this, he 
certifies that he has cured several glandered horses by means of 
his injections and fumigations thrown into the nostrils*.” 
LAFOSSE, JUNIOR, 1775, strongly advocating his father’s doc- 
trines, contended that the most conclusive and satisfactory evidence 
of their truth was afforded by repeated autopsies, and by the well- 
known experiment so often made by his father, as well as by him- 
self, of throwing corrosive injections upon the pituitary membranes 
of horses, and of so turning them glandered. He shaped his father’s 
pathology to the improvements medical science had in the interval 
undergone, and made some alterations in the divisions of glanders, 
calling them proper and improper — primitive and secondary — in- 
cipient, confirmed, and inveterate — simple and compound. He 
would not admit that the lungs participated in glanders, save from 
the supervention of pulmonic disease during its existence. But he 
allowed that the frontal and, occasionally, the maxillary sinuses, to- 
gether with the cornets and alee of the nose, partook of it. It was 
some time, however, before he discovered that the tumours under 
the jaw were not salivary, but lymphatic glandst. 
Malouin, 1761, appears amongst the earliest dissentients to the 
generally-received doctrine of Lafosse. He presented the French 
Academy with the results of his own observations, tending to 
shew that other parts, besides the pituitary membrane, became in- 
volved in disease; and that the longer the duration of glanders 
the greater the number of other tissues found affected by the 
disease;};. 
Gibson, 1754, describes glanders to consist in “ a malignant 
ulcer formed in the inside of the nose of the horse” — “ generally 
accompanied by a swelling of the kernels under the jaws. The 
matter discharged is, for the most part, either yellow or greenish, 
or tinged with blood ; and, when horses have been long glandered, 
that the bones and gristles are grown foul, the matter turns to a 
blackish colour, and becomes very fetid and stinking. And this is 
* Observations and Discoveries made upon Horses, &c. By Sieur La Fosse, 
Farrier to the King of France, 1755. 
t Dictionnaire Raisonn6e d’Hippiatrique, &c. Par. M. Lafosse (junior). 
Paris, 1775. 
I L’Abbe Rozier’s “ Dictionnaire d’ Agriculture Pratique.” 
