708 
THE HISTORY OF GLANDERS. 
charges from the head (where the case is of long standing, and the 
hone carious), they are equally incurable * .” 
St. Bel, 1792, the first Professor of the Veterinary College of 
London, adopted the opinions and practice of Lafosse on the subject 
of glanders ; and so, his experiments at Lyons, detailed here after 
his death, exhibit a series of nasal injections, united with antimo- 
nial and mercurial preparations by the mouth, &ct. 
COLEMAN, the LATE Professor, made a division of glanders 
into acute and chronic. “ That form or kind is acute which, like 
other acute diseases, proceeds regularly through its course and 
ends in death ; that chronic, which, so long as it continues so, will 
not destroy the animal. This is illustrated by what happens in 
chancre, bubo, and (venereal) gonorrhoea : one requires the adminis- 
tration of mercury, the other will in time run itself dry.” 
“ Acute GLANDERS may be defined to be, a specific inflamma- 
tion and ulceration of the Schneiderian membrane, more particularly 
of that part of it covering the septum, that appearing to possess 
a higher degree of sensibility . It is generally accompanied by 
tumefaction of the submaxillary lymphatic glands, which glandular 
tumour or tumours is simply the consequence of irritation.” 
“ By specific is meant, an inflammation not attended with the 
usual phenomena. If the inflammation could be as well recognised 
by any characteristic appearance as the ulceration is, then the 
horse ought to be pronounced glandered prior to the supervention 
of the ulcerative stage : to this there are analogous instances in the 
human subject. No surgeon decides on a case of syphilis before 
chancre makes its appearance, or on small-pox until pustules have 
formed. We may safely lay claim to two discoveries respecting 
glanders and farcy. One is, that the whole mass of blood has been 
found to be contaminated ; the other, that both diseases may be, 
and are commonly, produced without the agency of contagion. 
Mr. Hunter concluded that the blood was never in itself diseased, 
because he could inoculate with it in small-pox and syphilis with- 
out infecting the subject ; whereas, if he made use of lymph, he 
produced the disease. This is no proof, however, that the blood 
contains no morbific matter ; for the poison mixed with it may be, 
as we now know it to be, in too diluted a state to take any effect, 
though, in the purulent discharge, it appears to exist in a con- 
centrated form. On the same principle, a person may drink a tea- 
cup-ful out of a pail-ful of water containing a certain quantity of 
arsenic, with impunity ; but, should he take a quart or a gallon of 
* The Gentleman’s Stable Directory, by Wm. Taplin, Surgeon. 1791. 
f This account is taken from Mr. Blaine’s “ Outlines of the Veterinary 
Art,” fifth edition, 1841. 
