714 
THE HISTORY OF GLANDERS. 
decine Veterinaire,” in proposing to adopt names derived from 
human medicine for our veterinary ones in ordinary use, suggested 
for glanders that of “ affection contagieuse du systeme lym- 
phatique plainly shewing from this what his views were in 
regard to the pathology of glanders. 
Dupuy, 1817, whose celebrated work on Tuberculous 
DISEASE, commonly called glanders , consumption y strangles, farcy, 
Sfc., I was the first to introduce to the notice of my brother vete- 
rinarians in this country, occupies one of the highest stations in our 
present historical catalogue, as being the author of an entire new 
doctrine on the pathology of glanders, farcy, &c. Holding in little 
estimation the opinions of his predecessors, looking upon them as 
altogether insufficient to account for the phenomena exhibited in 
glanders and farcy, and resolved, if possible, to discover “ the 
source of the evil,” he traced the origin of both these diseases, as 
well as that of several others, not of horses only, but of dogs, cats, 
monkeys, and domestic fowls as well, to the existence and develop- 
ment of tubercle in some part or other of the body, and, accordingly, 
he ranged all these several disorders of the animals mentioned 
under the generic appellation of “ TUBERCULOUS AFFECTION.” 
“ Tubercles, which appear as little, firm, grey, hard bodies, are 
organic productions, originating from causes unknown, existing at 
first in small numbers, and interfering but little with the functions 
of the parts generating them. In this, their incipient state, the 
animal enjoys perfect health, and continues in the preservation of it 
up lo the period of the disorganization of the tubercle, those changes 
in its interior which end in its mortification and ulceration. In time, 
they increase in number, and the result is a discharge commonly 
from one nostril, which, at its commencement, is regarded as catarrh 
or strangles. This stage may occupy a term of five or six years* 
In the second stage the tubercles grow soft, break, and become con- 
verted into ulcers. There are varieties of tubercles; the most 
common are the miliary ; and these are the precursors of that 
species of ulceration which I have described (at page 169) as re- 
sembling worm-eaten wood. They are found in greatest numbers 
in the course of the large veins upon the septum. They are 
also found within the duplicature of the ala nasi, and upon the 
turbinated bones, pursuing the course of the large bloodvessels. 
They may even exist within the substance of the cartilage of the 
septum, and thus assist in its destruction. The membrane lining 
the sinuses is rarely found tuberculated. Tubercles have, however, 
been observed in the lungs, lymphatic glands, cellular membrane, 
* Dupuy cannot exactly say how long : once developed, however, resolution 
is hopeless. 
