720 
THE HISTORY OF GLANDERS. 
such matter have had tubercles produced in their lungs in the 
space of five days ; and what renders this experiment more satis- 
factory, is, the fact of asses rarely having (from other causes) 
tubercles in their lungs. 
YOUATT regards glanders as “ inflammation of the Schneiderian 
membrane, strictly local for awhile, and during its insidious state; 
and even when the discharge becomes gluey, and some time after 
chancres have appeared, the horse is apparently well.” — “ I can- 
not say,” continues Mr. Youatt, “ that glanders, like the rot, im- 
proves the condition ; but I have seen that often, and for a long 
while, for months and even for years — it does no injury to the 
general health. The inflammation is purely local, and is only 
recognized by that invariable accompaniment of inflammation, — in- 
creased secretion. Although that secretion is poisonous, and its 
neighbours fall victims to it, it affects not the animal whence it 
came. But this continued inflammation at length tells, or other 
circumstances increase its power and its effect, and the vitality of 
the tissue is destroyed and suppuration succeeds; but not that of a 
healthy character — not that which is connected with reproduction ; 
— it is malignant and destructive from the beginning ; and soon 
another process commences, salutary or destructive, according to 
circumstances. There are absorbents on every surface ; they are 
found on the surface of the chancres which are beginning to appear ; 
and they take up the fluid which is secreted from the ulcers, and 
they soon feel its poisonous influence. The absorbents become in - 
flamed and tumid, and, where the virus rests, as it were, viz. at 
the valves, destruction of the part ensues, and the chancres spread 
in every direction.” — “ Some portion of the venom passes on, and 
is carried into the circulation and mixes with the blood, and vitiates 
the blood.” — “ Then comes the constitutional affection. The mem- 
branes of the neighbourhood, and those most susceptible of irrita- 
tion, first yield. Chancres proceed down the pharynx and larynx, 
and gradually the ulcers spread over the frame. The acrimonious 
fluid, mingling with the blood everywhere, begins everywhere to 
attack that tissue which is most susceptible of its influence, viz. 
the lining membrane of the absorbents and by degrees, and in 
most distant parts of the frame — the hind extremities are a favourite 
situation — the absorbents become chorded, and tumours appear in 
the situation of the valves, and ulcerations ensue. First, the super- 
ficial absorbents are affected ; then the deeper-seated become in- 
volved : the whole frame is empoisoned ; farcy is established in its 
most horrible form, and death speedily closes the scene*.” 
Vines, 1833, deserves the thanks of the profession for the pains 
he has taken in the practical investigation of a subject, some of the 
* Mr. Youatt’ 3 Veterinary Lectures in The Veterinarian for 183:2. 
