KFFECTS OF MEDICINE ON HORSES. 
49 
commenced, and the catharsis continued during the whole of the 
following day. Indeed, the effect proved fully equivalent to 
what an ounce of aloes would have produced. 
November 5th, 18*22. — The same (glandered) horse who had 
been made the subject of experiment in testing the effects of Ep- 
som salts took this morning the same dose (Ifeiss) of castor oil as 
had been administered in the last case, of which not above half- 
an-ounce was wasted. At six o’clock the same evening his dung, 
which had been hitherto falling in balls, was observed to fall in 
divided portions, as though preparatory to purgation. On the 
morning of the 6th, however, no purgative effect had followed ; 
neither had there been observed any sign of nausea, dispirited- 
ness, or disinclination for food. — 1th, as usual. No effect what- 
ever could be detected. 
April 23<7, 1 822. — At half-past nine o’clock in the morning a 
pint of castor oil was given to a large bay horse, standing in the 
infirmary on account of an incurable farcinous affection of the near 
hind limb ; he having been prepared for the dose by a bran-mash 
over night and the withdrawal of his hay. After taking his oil 
he was, in the course of the day, thrice walked about for exercise. 
At eight o’clock P.M. he had shewn no signs of purging, but he 
exhibited dulness and languor and impairment of appetite, and 
some augmentation of pulse. At seven o’clock at night these symp- 
toms had become more manifest, and his pulse now was 70. At ten 
o’clock P.M. we found him standing “all of a heap,” with his hind 
limbs advanced underneath his body, and his abdomen sensibly 
contracted and tense, indicative of pain, although such was not, 
further than this, actually expressed. 
24?/i. — He has not eaten much during the night, but this morn- 
ing has drunk two pails-ful of (chilled) water. Does not purge, but 
still stands in the crouching position he did last night, and his belly 
continues tense and drawn up; and when walked out, he moves his 
limbs as though cramp or rheumatism had seized them all. All 
this makes us think the animal must be suffering a good deal of 
inward uneasiness — not to say, pain — although, as yet, he has 
evinced nothing of the nature of “ gripes.” In the course of the 
afternoon he was found lying down, with his body and limbs 
stretched out, and occasionally grunting. He has eaten very lit- 
tle to-day, but drinks freely. Let him have a purgative enema 
every two hours. At seven o’clock P.M. still lying, and now with 
his legs drawn together towards his abdomen. He seems now 
very uneasy : he is making occasional efforts to rise and then 
falls down again, as though he had not the power of erecting his 
body. At length, however, he accomplished it; and no sooner 
was upon his legs than he passed a copious liquid evacuation — - 
VOL. XVIII. H 
