170 
ON THE TRANSMISSION OK SOME MALADIES 
the sheep, this disease shews itself under a new appearance, — its 
march being more rapid, and the vaccine virus having altered and 
lost its anti-variolous property. 
Every one has heard of that fearful disease canine madness, 
susceptible of being spontaneously developed in the carnivora, the 
dog, and the wolf. That these animals are enabled by their bite 
to transmit the virus to man, is attested by a great number of 
examples. The rabid virus appears to reside in, or to be nothing 
more than an alteration of, that fluid. 
M. Renault has impregnated a lancet with the saliva of a rabid 
dog, which he passed under the epidermis of a horse. At the 
expiration of eighty-six days this horse became rabid. Before 
him, MM. Magendie and Breschet had inoculated two dogs with 
the saliva taken from two others, one of which became rabid eight 
days afterwards. 
Glanders appears both in an acute and chronic form. In the 
last state it used to be regarded as exceedingly contagious, but of 
late it has not been considered as much so ; in fact, many veteri- 
narians say that there is no such thing as chronic glanders. 
As to acute mange, it is very different. It is justly considered as 
contagious between animals of the same kind, — the horse, the ass, 
and the mule. How is it with regard to the human being] That 
is a question undecided. The facts which present themselves in 
favour of contagion are neither sufficiently numerous nor precise 
to decide the matter. 
There have been cited in the journals some cases of the commu- 
nication of chronic glanders from the horse to man. These cases 
passed in a manner unperceived ; but there was one that made a 
great impression, both for and against, in 1837. 
M. Ratier spoke of a singular malady of which a man of the 
name of Prot perished, after lying in a stable in which was a mare 
affected by both farcy and glanders. The greater part of the aca- 
demicians thought that the disease of Prot was the result of the 
contagion communicated from the man. They gave it as their opi- 
nion, that it differed from all the diseases that had been known to 
affect the human being ; yet it did offer some analogy with the 
symptoms and lesions of glanders and farcy. Some matter was 
procured from the pustules of this man, and a horse was inoculated 
with it ; the consequence of which was an ulceration, which they 
believed to be glanders. 
M. Barthelemy, in a brilliant address, declared that he did not 
see any resemblance between the disease of Prot and the glandered 
state of the horse. He and M. Bouley were astonished that such 
a transmission could be considered possible, when the annals of vete- 
rinary science did not contain a single example of the kind. The 
