PROGRESS OF VETERINARY SCIENCE AND ART. 147 
of Sciences in Paris, in which it was announced that he had 
succeeded to communicate, by inoculation, syphilitic ulcers 
to the monkey, the cat, the rabbit, and dog. The scientific 
curiosity of French syphilographers thus awakened, some of 
them undertook to repeat the experiments of Auzias-Turenne : 
amongst others MM. Castelnau and Cullerier recorded the 
results obtained, and both agreed in not having communicated 
in any way the syphilitic ulcers to any of the lower animals. 
Auzias did not despair, even after this discouraging publica- 
tion ; repeating the experiments, he convinced himself of the 
possibility to transmit syphilis to the brute creation, by ob- 
serving certain necessary precautions. He laid before the 
members of the academy two monkeys in which ulcers had 
formed, bearing all the characters of Hunterian,* secreting 
pus, the inoculation of which gave origin to ulcers of a similar 
nature. Notwithstanding all this, he had not been able to 
inspire, in the greater part of his colleagues, that certainty, 
that conviction, which he had hoped. It was necessary to 
have a decisive, peremptory experiment, to set at nought 
those who would not believe in it. If the inoculation of the 
pus of an ulcer produced on a brute would cause the develop- 
ment of a similar ulcer on man, the question would have been 
solved. Auzias therefore appealed to all who believed in the 
localization of the primitive signs, that in the interest of 
science they should submit to the essay. For a long time no 
one obeyed the voice, till Professor Weltz, in 1850, decided 
to attempt the proof on himself. Having taken pus from 
ulcers developed on a monkey, and on a cat, he inoculated 
himself in four places on the arms, and in all four he obtained 
the specific ulcer with all its characters, which he allowed 
freely to develop for the first ten days, after which he cured 
them by repeated cauterization.” 
“ In the following year, Diday (of Lyons) inoculated himself 
on the penis with pus from a primitive ulcer in a cat ; the 
inoculation was followed by an ulcer which became phage- 
dsenic, and gave serious apprehensions to this courageous and 
distinguished colleague.”t 
<c With these facts, no adverse criticism can avail. Hence- 
* Some of my readers may not know what is a Hunterian chancre , not 
having to study the diseases of man ; it is a syphilitic sore with indurated 
edges and base, the hardened swelling around and beneath it due to a 
peculiar plastic effusion ; it differs thus from the simple chancre or chancrous 
excoriation and the phagedcenic or sloughing chancre , peculiarly destructive 
and dangerous. 
f Here Sperino, gives a long note, in which he says, that Sigmund, 
Clinical Professor of Venereal Diseases, in Vienna, obtained positive results 
from the inoculation of the virus in all warm-blooded animals, and in the dog, 
