VESICULAR DISEASE CONTRACTED FROM SHEEP. 473 
piece. Around each of’ the bullae the cutis seemed inflamed. 
A few were now observed on the hairy scalp. The eruption 
was seen about the hands, around the wrists, extending up 
the inner aspect of the forearms. A similar eruption was 
also detected in each iliac region, the inner aspect of the 
thighs, upon the scrotum, upon the penis, and upon the back 
of the trunk ; also upon each foot, about the ankle, and along 
the tarsus. Some of these bullae were very minute, and 
others larger, about the size of split peas. As 1 have already 
said, the eruption was confined to the finer parts of the skin ; 
in those parts where the cuticle was thickened, — on the outer 
aspect of the arm and thigh, the palms of the hands and soles 
of the feet, — this vesicular eruption was absent. The wound 
in the thumb was open, and discharging. The constitutional 
disturbance was much less than might have been expected 
to accompany such an extensive eruption. He was evidently 
a youth of great courage, and made light of his pains. His 
breathing was easy. There was slight cough and sore throat. 
Skin hot and dry. Tongue coated on the dorsum with a 
thickish white fur, the edges presenting an appearance of 
having small pimples upon them. Has a tolerable appetite ; 
is not sick ; no headache, and no thirst ; bowels not open ; 
urine free. 
Now, I shall not pursue this case day by day, through its 
progress, but I will read you the note of the day after his 
admission, and then I will tell you generally the progress of 
the case for the ensuing fortnight. We found on the follow- 
ing morning that he had slept but little in consequence of the 
discharge from the eyes, which had been constant all night. 
His expression was anxious. He w r as lying on his back, w ith 
his mouth open. Lips and teeth dry. On the internal lining 
of the low er lip w-e observed a number of these minute vesi- 
cles, and some w-ere to be seen on the soft palate, which had 
the appearance of being covered with patches of slough. 
About his face there were numerous bullae, especially below 7 
the chin, and these had now begun to desiccate. About the 
upper extremities — on the inner aspect w^here the skin w 7 as 
soft — there was an appearance of these bullae and vesicles, 
they were so numerous and congregated so closely together 
as to have become completely confluent. You could have 
fancied that the skin had been scalded with boiling water. 
About the thorax, also, the spots w 7 ere more numerous, some 
of them containing fluid, which on the previous day they did 
not contain. They w 7 ere more numerous about the trunk, 
about the axillae and back, and in the iliac regions, the groins, 
the inner aspect of the thigh, and over the scrotum. Some of 
xxix. 6l 
