THE PATHOLOGICAL HISTORY OF GLANDERS. 311 
the finger has been injured, pain and swelling almost invariably 
set in within a very brief interval, followed by red streaks and 
retiform spots along the skin. 
“ The lymphatic glands at the bend of the arm and in the axilla 
become painful, and partially suppurate ; in short, all the conse- 
quences of inflammation of the absorbents ensue : occasionally, the 
marks of phlebitis are apparent. 
“ The original wound turns either to an ill-conditioned sore, or 
else healed up for a time, and then bursts open afresh on the 
period of incubation terminating. 
“ However the disease may originate, it makes rapid progress, 
usually proving fatal within a fortnight or three weeks. It be- 
comes chronic only when complicated with farcy, and contracted 
by inoculation from horses labouring under like complication. 
“ The symptoms of farcy, namely, cutaneous eruptions and 
ulcers, together with abscesses in the subcutaneous cellular tissue, 
and between or in the substance of the muscles, gradually spreads 
from the injured parts over the entire limb, and ultimately over 
the rest of the body. Glanders then supervene, with concomitant 
fever, and the trains of disturbance above described. 
“ In Rayer’s Researches it is shewn that simple farcy is equally 
communicable to man, and destroys life both in its acute and its 
chronic stage. 
“ Both in glanders and in farcy, whether acute or chronic, it is 
sometimes no easy matter to determine, either from the history of 
the case or from the results of dissection, whether some of the 
appearances, as lobular pneumonia, purulent deposits within the 
lungs, muscles, joints, &c. be not rather due to simultaneous in- 
flammation of the lymphatics and veins, with absorption of pus 
into the circulation, than to the original disease. Sometimes the 
returning vessels have been found perfectly healthy, — in some few 
instances decidedly inflamed, — and in many their condition does 
not seem to have met with due consideration and attention. 
“Recently, Engel* has contended against the possibility of 
the transfer of glanders from horse to man ; and seeks to prove, by 
the aid of numerous skilful dissections of glandered carcasses, that 
the disease is identical with tubercular mischief. The rise, pro- 
gress, and termination of the local affection, the form of the ulcers, 
and many other circumstances, certainly offer many points in sup- 
port of such an hypothesis.” 
This tubercular hypothesis we consider but a very approxima- 
tive one, seeing that the special semiology of glanders and tubercu- 
losis is very dissimilar. 
* Oesterreich, Medicinische, Wochenschrift, 1842. 
