568 
COMPTE RENDU OF THE 
3. Strangles also occasionally engenders glanders. This happens 
when the fluxional commotion, of which the head is the seat in the 
former of these diseases, is propagated to the membrane of the sinus, 
and gives rise to the formation of a purulent collection in one of 
the cavities, which eventually becomes the source of an inexhaustible 
running. 
4. Glanders frequently attacks horses having every advantage 
that breed, sound constitution, goodness of form, light work, whole- 
some feeding, and salubrity of stabling, can bestow. 
5. Glanders exists but in two stages, the acute and the chronic ; 
gangrene does not constitute any peculiar variety of glanders, but 
is simply a termination of the acute stage. 
6. These two stages of glanders are often confounded in the same 
patient ; either the chronic stage succeeds to the acute, or the acute 
stage grafts itself on the chronic : hence, in practice, it is frequently 
impossible to distinguish between the two stages. 
7. The attack of glanders, whatever may be the form it is sub- 
sequently to assume, is always preceded by a pyretic state, which 
lasts from three to nine days. 
8. This fever of incubation does not always develop itself under 
purely pathognomonic characters. An extreme depression — loathing 
of all kinds of solid food — heat, adherence, dryness, and scurfiness 
of skin — dead and rough coat — small, quick, and contracted 
pulse — rapid and uncertain breathing — tottering and methodical 
gait — a rapid and almost instantaneous loss of flesh ; such are the 
vague and indefinite symptoms which lead us to dread the outbreak 
of glanders, especially in working horses, unless an examination of 
the viscera enables us to attribute all this to the commencement of 
some organic lesion. 
9. Glanders at the commencement, whatever may be the type 
under which it afterwards develops itself, always begins with 
symptoms of acuity : post-mortem examinations prove this. 
10. The pyretic state diminishes or ceases entirely as soon as 
the disease commences*. 
down great heights into deep excavations, have become glandered after a lapse 
of three, four, or five weeks, although, at first, the fall did not appear to have 
caused any serious organic lesion, or even to have impaired the general func- 
tions. We merely state this fact without, at present, making any attempt to 
explain it. 
* This almost invariable and insidious phenomenon is frequently the cause 
of very dangerous errors. On perceiving the apparent improvement which 
suddenly manifests itself at the moment of the invasion of the disease, the 
owners of the animals are but too apt to deceive themselves with the hope of 
soon seeing that which they believe to be but a slight fit of indisposition, 
perfectly cured; while, in point of fact, the disease is then but just breaking 
out, and is more dangerous than ever. 
