VETERINARY SCHOOL AT ALFORT. 
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24. Chronic glanders ought, in order to become contagious, to 
change its character under the influence of work, and the fatigue 
thereby occasioned. Charbon, with all its contagious characteris- 
tics, develops itself in a few hours in over-driven or worked oxen : 
acute glanders will suddenly appear in a most startling manner, 
and in animals of the very best constitutions, in consequence of 
over-work. Why should not chronic glanders develop itself in a 
similar manner, and still more so in horses already under the in- 
fluence of as serious a disease, and one which leaves upon their 
constitutions so deep a stain as that of chronic glanders* ! 
25. Admitting the possibility of the contagiousness of chronic 
glanders, that is to say, that it is practically so, the sanitary laws 
and regulations ought to be most strictly observed with regard to 
all animals affected by it. But, in order to take a reasonable view 
of such matters, we must not make a bugbear of this contagion, 
and attribute to it consequences which may be logically shewn to 
arise from other causes. 
The denial of the contagiousness of glanders by so many ob- 
servers is, at any rate, a proof that its contagious properties are not 
so evident, and consequently so dangerous, as some would have us 
believe. 
26. Acute and chronic glanders may become spontaneously 
cured when the animals are in good hygienic conditions. The 
therapeutic means to which recourse is had to combat these affec- 
tions are only efficacious to repair the local lesions, when the 
germ of the evil which produced them has become completely ex- 
hausted. 
27. Acute and chronic glanders can only disappear from a 
spontaneous effort of the organism, when the lesions which they 
have occasioned at the period of their eruption are limited, and are 
extinct on the membranes in free communication with, and exten- 
sively and normally open to, the exterior. 
Thus, glanders may become cured when the pustulous eruption 
takes place in the large openings of the nostrils, on the surface of 
the partition, or on the exterior of the ales nasi. It may also be- 
come cured when the eruption appears on the surface of the body ; 
but it becomes incurable when, under the influence of the glander- 
banished. The cohabitation has lasted some weeks, some months, and even 
for a whole year, and we have been unable to perceive any case of contagion. 
* Facts appear to us to militate more and more in favour of this opinion. 
A serious and painful operation which induces a high degree of fever will 
cause chronic glanders to pass rapidly into an acute state ; and under similar 
circumstances a healthy horse may suddenly become affected with acute 
glanders. Scarcely a month ago we saw this disease manifest itself in a most 
sudden and striking manner in a ten-year-old horse of sound constitution, 
which had been suffering from a most painful traumatic lesion of the hoof. 
