572 
COM PTE RENDU OF THE 
ous crisis, the cavities of the alae nasi and the sinuses of the head 
are filled with pus ; when the lungs, the spleen, the liver, are be- 
spattered with ulcerations; when the articulations contract sup- 
purative action under the influence of specific inflammation; when 
the principal lymphatics of the limbs have become obstructed 
through the pus they convey. In a word, whenever the glanderous 
eruption gives birth to organic lesions, it, by this action, sets at 
naught the power of nature and art, and becomes incurable. 
28. Another necessary condition to the possibility of a spon- 
taneous cure of glanders is, that its eruption should be moderate. 
Where the glanderous pustules are confluent, they create a dispo- 
sition to gangrene in the limb on which they appear (the mucous 
membrane and external tegument), and the lesion thus produced 
by them becomes as incurable as if the pustules had been deep- 
seated*. 
29. All those specifics that are cried up as infallible cures for 
glanders are useless. It is folly to attempt the cure of this affec- 
tion excepting under the conditions we have pointed out : there is 
a natural and spontaneous cure of chronic glanders even where 
there is complication of the disease with a purulent collection of 
matter in the sinuses, and hence may have arisen the illusion rela- 
tive to the beneficial effects of certain therapeutic agents which 
have been employed to combat this affection. Occasionally, after 
the lapse of a considerable period, months or even years, the sinuses 
have thrown off the pus they contained, and the membrane cover- 
ing them secretes an apparently albuminous matter which becomes 
concreted, organises, and fills up the whole of the purulent cavity. 
The consequence of this transformation of the membrane of the 
sinuses is the drying up of the discharge. This is one of the very 
rare terminations of chronic glanders complicated with a purulent 
collection in the sinuses. 
30. The best method of treating local glanderous eruption is to 
apply the actual or potential cautery, or to extirpate the diseased 
part. The extirpation of glanderous sarcocele is attended with 
greater or less success, according as the operation is performed 
sooner or later after the commencement of the evil. If the sole 
object of the operation were to get rid of a source of excessive 
pain and irritation, it would be rational and advisable. When 
about to practise it, we ought always to wait until we see acute 
* In the course of this year we saw the entire skin of one limb become 
literally gangrenous in consequence of the sudden eruption of acute glanders. 
Notwithstanding the glanders had confined its action to that part, that the 
nose and chest were perfectly healthy, and the patient retained his appetite, 
he fell into a complete state of etisy, arising from the enormous quantity of 
suppuration which was discharged from so extensive a suppurating surface as 
the entire periphery of a limb. It became necessary to destroy him. 
