22 
DEFECTS OF MEDICINE ON HORSES. 
21^. — Notwithstanding the gij doses were persevered in, his 
appetite has recovered ; therefore now give Jiij twice a-day. 
2 3d . — §iv twice a-day. 
24 th. — Jiij twice a-day. The supply of the medicine being ex- 
hausted, the dose was necessarily reduced. 
2 Jib had been taken in ten days, and the only visible effects such 
large doses had produced was impairment of the appetite ; until 
latterly, when soon after taking his medicine, he exhibited symp- 
toms of giddiness in the head, and while at exercise was reported 
by the man who rode him to stagger about. 
STAVESACRE — Delphinium Staphisagria* . 
ThORNAPPLE — Datura Stramonium. 
Nov. 2, 1812. — A chestnut horse, glandered, but in good work- 
ing condition, and with good appetite, commenced taking Jj twice 
a day of the dried leaves of stramonium. 
3 d. — Dose augmented to Jij twice a-day. 
4 th. — Jiv twice a-day. 
5th. — Yesterday’s large doses have taken away his appetite. 
Nevertheless, they are repeated to-day. 
6th. — Refuses all food; is dull, and appears very unwell. The 
stock of medicine being, however, unfortunately expended, I am 
unable to prosecute the experiment. 
TOBACCO — Nicotiana Tabacum. 
In the month of January 1805, there arrived at Woolwich ten 
horses which, on examination by my father, were found confirmedly 
glandered. It was recommended that tobacco be made trial of in 
the form of fumigation : accordingly, a fumigating apparatus was 
procured, and they were all submitted, morning and evening, to its 
operation. After a week’s fumigating, in three of the cases there 
appeared abatement of the nasal discharges. The discontinuance, 
however, of the fumigation for a few days was followed by their 
return in the same profusion as before. This was the only ob- 
servable effect the fumigation had on their disorder. 
The symptoms produced by the fumigation, more remarkable in 
some than in others, were, disturbed respiration, increasing in some 
cases to apparent signs of suffocation, giddiness, and stupor; the 
appetite was not affected, neither were the operations of the kid- 
neys or bowels disturbed. 
The fumes of tobacco are at the present day employed with 
striking advantage in cases of obstinate constipation from 
colic, &c. 
* For the effect of stavesacre on glandered horses, consult the author’s 
“ Ilippopathology,” vol. iii, p. 340. 
